New plasma injection may ease spinal headaches

NCT ID NCT06790745

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested two treatments for headaches that can happen after a spinal tap. One treatment uses a person's own blood (epidural blood patch), and the other uses a special substance made from their blood (plasma-rich fibrin). The goal was to see which works better to relieve the headache. Sixty adults with this type of headache took part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Plasma-rich fibrin

What this could lead to

If successful, this could offer a new treatment option for post-dural puncture headache, potentially with fewer side effects than the standard blood patch.

What could go wrong

This is a small, completed study with only 60 participants. Results may not apply to everyone, and the new treatment might not be more effective than the existing one.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

intracranial hypotension Post-Dural Puncture Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tanta University

    Tanta, El-Gharbia, 31527, Egypt