Inherited epidermolysis bullosa

This small early-phase trial tested an experimental drug called rigosertib in just 2 people with a rare blistering skin disease (recessive dystrophic epidermolysis bullosa) who also had advanced skin cancer. The goal was to see if the drug could shrink tumors and whether it was s…

This study tested whether cannabidiol (CBD) can reduce severe itching in 10 children with a rare genetic skin condition called epidermolysis bullosa. The children took CBD syrup three times a day for a month. Researchers measured itch, pain, sleep, and quality of life before and …

This study tested whether a numbing cream (ropivacaine) can reduce severe pain during bath and dressing changes in children and young adults with epidermolysis bullosa, a rare genetic skin condition. Ten participants applied the cream before dressing changes and reported their pa…

This pilot study tested a portable device called Spincare that sprays a nanofiber dressing onto wounds in people with recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic condition causing fragile, blistering skin. Six participants with at least six chronic or recurr…

This study looked at whether specialized training for nurses on how to care for children with a rare, severe skin condition called epidermolysis bullosa (EB) can reduce their stress and anxiety. The study involved 19 nurses and nursing assistants at a hospital in France. Research…

This study looked at why children with hereditary epidermolysis bullosa (a rare condition causing fragile skin and painful blisters) often do not take prescribed opioid painkillers before baths and bandage changes. Researchers interviewed 10 children and their parents to understa…

This study looked at how skin cells from 30 people with recessive dystrophic epidermolysis bullosa (RDEB) grow and repair wounds. RDEB is a rare genetic condition that causes fragile skin and painful blisters. Researchers took small skin samples to study the cells in a lab, aimin…

This study tested an artificial intelligence algorithm designed to help primary care doctors decide whether a patient with a skin condition really needs to see a dermatologist. Researchers enrolled 200 adults with skin problems and had their doctors take photos of the affected ar…

This study tested two different ways to remove leftover glue from teeth after braces are taken off. 142 people who had braces or clear aligners were split into two groups: one used a special ultrasonic tool, the other used a polishing bur. Researchers checked plaque, bleeding, le…