CBD oil may soothe itch in kids with rare skin disease

NCT ID NCT05651607

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether cannabidiol (CBD) can reduce severe itching in 10 children with a rare genetic skin condition called epidermolysis bullosa. The children took CBD syrup three times a day for a month. Researchers measured itch, pain, sleep, and quality of life before and after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cannabidiol (CBD) oral solution
What this could lead to
If it works, CBD could offer a new way to relieve severe itching and improve quality of life for children with this rare skin condition.
What could go wrong
This is a very small, early-phase trial with only 10 children, so results may not apply to everyone. CBD may cause side effects, and the itch relief might not last.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Necker Enfants Malades

    Paris, 75015, France

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