Hereditary otorhinolaryngologic disease

This pilot study aimed to test whether a mixture of dexamethasone, hyaluronic acid, and a green dye could be safely injected into the ear to treat certain types of hearing loss that don't improve with standard treatments. The plan was to enroll 26 adults with sudden hearing loss,…

This study tests whether a cochlear implant can safely and effectively restore hearing in people who become deaf in one ear after surgery to remove a benign tumor (vestibular schwannoma) or to treat Meniere's disease. Fifteen participants will receive the implant during their sur…

This early-phase study is testing whether stem cell therapies and experimental drugs can help repair inner ear damage in people with hearing loss or tinnitus. Researchers will monitor 120 adults over time using hearing tests and symptom surveys. The goal is to see if these regene…

This study tests a fully implanted cochlear implant called Acclaim CI in 56 adults with severe to profound hearing loss. The goal is to see if it helps them hear words better than before and to check for any medical problems. Participants get the implant and are followed for up t…

This study tests whether a personalized, data-driven hearing rehabilitation program can improve hearing, thinking, and quality of life in older adults with mild to moderate hearing loss. Two hundred first-time hearing aid users will be randomly assigned to either the new personal…

This study tests two types of exercises to help people who get dizzy, nauseous, or have blurry vision from using computers for long hours. 46 computer users will do either head-movement or eye-movement exercises for 4 weeks. The goal is to see which exercise better reduces sympto…

This study tests whether adding balance training, education, and vestibular rehab to the standard Epley maneuver helps people with benign paroxysmal positional vertigo (BPPV) more than the maneuver alone. Forty-six adults with BPPV will receive either the combined approach or sta…

This pilot study aimed to test whether immersive virtual reality (VR) exercises could help people with multiple sclerosis who experience dizziness, balance issues, and fatigue. Participants would have been randomly assigned to either VR-based vestibular rehab or conventional exer…

This phase 3 trial tests an oral drug called tradipitant in 705 adults with a history of motion sickness. The goal is to see if it is safe and can ease symptoms during real travel. Participants take the drug before or during trips, and researchers monitor side effects and how wel…

This study tests a wearable device that uses mild electrical stimulation on the head to reduce motion sickness during virtual reality (VR) simulations. Forty adults aged 21-55 will participate at the Mayo Clinic in Arizona. The goal is to improve the technology so people can enjo…

This study tests two different head-and-body rotation procedures done in a mechanical chair to treat a common inner-ear condition called BPPV, which causes brief but intense spinning sensations. 128 adults with confirmed BPPV will be randomly assigned to either the standard Epley…

This study looks at how virtual reality affects stroke patients, specifically checking for motion sickness. Researchers will measure heart rate, blood pressure, and use a special questionnaire to see if VR causes discomfort. The goal is to understand and improve the use of VR in …

This study looks at children having surgery to remove a common neck lump called a thyroglossal duct cyst. Some kids will have a small drain placed during surgery, and some will not. The goal is to see if using a drain reduces problems like infection, fluid buildup, or the need fo…

This study planned to test whether playing specially designed video games at home could improve the ability of older adults with high-frequency hearing loss to understand speech in noisy environments. Participants would have played either an immersive audiomotor game or an audito…

This study aims to learn more about diseases that affect the brain, such as Parkinson's disease and different types of dementia. Researchers will follow 500 adults with symptoms of these conditions over time, using brain scans and genetic tests to see how the diseases progress. T…