Can 3D imaging sharpen the diagnosis and surgery of a common hearing condition?

NCT ID NCT05921578

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study investigates whether cone-beam computed tomography (CBCT), a 3D imaging technique, can improve the diagnosis and surgical treatment of otosclerosis, a condition where abnormal bone growth in the middle ear causes hearing loss. Researchers will enroll 100 adults suspected of having otosclerosis to measure how accurately CBCT detects the disease and how well it helps surgeons plan the placement of a prosthetic device during stapedotomy, a corrective surgery. The study also tracks hearing outcomes after surgery to see if CBCT-based planning leads to better results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cone-beam computed tomography (CBCT) imaging of the temporal bone
What this could lead to
If CBCT proves accurate, it could become a standard tool for diagnosing otosclerosis and planning stapedotomy, potentially improving surgical precision and hearing outcomes.
What could go wrong
This is a diagnostic accuracy study, not a treatment trial. CBCT may not outperform current methods, and its impact on surgical success remains uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rigshospitalet

    Copenhagen, Denmark

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