Could a pill end motion sickness for good?

NCT ID NCT06138613

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests an oral drug called tradipitant in 705 adults with a history of motion sickness. The goal is to see if it is safe and can ease symptoms during real travel. Participants take the drug before or during trips, and researchers monitor side effects and how well it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tradipitant (oral capsule)

What this could lead to

If it works, this could provide a new medication option to prevent or reduce motion sickness during travel.

What could go wrong

This is an open-label study (no placebo), so results may be biased. It is still experimental, and side effects or lack of effectiveness are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

motion sickness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Santa Monica Clinical Trials

    Santa Monica, California, 90404, United States