Vanda Pharmaceuticals

This study tests an experimental drug called ponesimod in 300 adults with moderate-to-severe plaque psoriasis. The goal is to see if it is safe and helps control the disease. Participants take the drug and are monitored for side effects and skin improvement.

This early-stage study is testing whether a drug called trichostatin A is safe for people with blood cancers that have returned or not responded to standard treatments. About 42 adults will receive the drug through an IV to find the highest safe dose and watch for side effects. T…

This study tests whether iloperidone, a drug already used for schizophrenia, can help lower blood pressure in people whose hypertension is not controlled by their current medications. About 240 adults will receive either iloperidone or a placebo for 4 weeks, and researchers will …

This study tests whether a long-acting injection of iloperidone can delay or prevent the return of schizophrenia symptoms compared to a placebo injection. About 400 adults with schizophrenia who need ongoing treatment will receive either the drug or a placebo and be monitored for…

This phase 3 trial tests a single oral dose of VQW-765 versus placebo for quickly reducing acute anxiety in adults with social anxiety disorder. About 500 participants will take the drug as needed before anxiety-provoking situations. The study measures distress levels during and …

This study tests whether a daily dose of tasimelteon helps children aged 2 to 17 with insomnia fall asleep faster and sleep better. About 420 participants will receive either the drug or a placebo. The goal is to improve sleep and daytime functioning without serious side effects.

This Phase 3 study tests whether tradipitant can reduce nausea and vomiting caused by GLP-1 weight-loss drugs. About 280 healthy overweight or obese adults will receive either tradipitant or a placebo. The goal is to see if tradipitant helps people tolerate these medications bett…

This Phase 3 study tests whether adding milsaperidone to standard antidepressant therapy helps adults with major depressive disorder who still have symptoms. About 500 participants will receive either milsaperidone or a placebo, and researchers will measure changes in depression …

This Phase 3 trial tests whether the drug tasimelteon can help people with Delayed Sleep-Wake Phase Disorder (DSWPD) fall asleep earlier and sleep better. 70 adults with DSWPD will receive either tasimelteon or a placebo daily. The study measures sleep onset and quality using sle…

This study tests whether a new eye drop called VSJ-110 can safely ease dry eye symptoms. About 160 adults will use either the active drops or a placebo for eight weeks. Researchers will check for changes in eye surface damage, tear production, and discomfort.