Vanda Pharmaceuticals

This early-stage study is testing the safety of a drug called trichostatin A in adults whose blood cancers have returned or stopped responding to standard treatments. The main goal is to find a safe dose and understand side effects. About 42 participants will receive the drug and…

This study tests an investigational drug called iloperidone for people whose high blood pressure remains high despite taking one or more standard medications. About 240 adults will receive either iloperidone or a placebo for 4 weeks to see if it safely lowers blood pressure furth…

This study tests whether a new drug called milsaperidone can help adults with major depression who haven't gotten enough relief from their current antidepressant. About 500 people will receive either milsaperidone or a placebo pill alongside their usual medication. The main goal …

This study tests whether tradipitant can reduce nausea and vomiting caused by popular weight-loss drugs (GLP-1 agonists) in 280 overweight or obese adults. Participants will receive either tradipitant or a placebo and track their symptoms daily. The goal is to help people stick w…

This study tests whether a daily pill called tasimelteon can help people with delayed sleep-wake phase disorder (DSWPD) fall asleep earlier and sleep better. About 70 adults with DSWPD will receive either the drug or a placebo for several weeks. The goal is to see if the treatmen…

This study tests a single-dose pill called VQW-765 to see if it can quickly reduce acute anxiety in adults with social anxiety disorder. About 500 participants will receive either the drug or a placebo before a stressful social task. The goal is to measure distress levels during …