Vanda Pharmaceuticals

This Phase 3 trial tested a drug called imsidolimab in 45 adults with generalized pustular psoriasis (GPP), a rare and severe skin condition that causes painful pustules. Participants received either a single intravenous dose of imsidolimab (750 mg or 300 mg) or a placebo. The ma…

This phase 2 trial tested a drug called imsidolimab (ANB019) in 149 people with hidradenitis suppurativa, a chronic skin condition causing painful abscesses and nodules. Participants received either the drug or a placebo to see if it could reduce the number of inflamed lesions. T…

This Phase 2 trial tested a drug called imsidolimab (ANB019) in 123 people with moderate to severe acne. The drug is a lab-made antibody designed to reduce inflammation. Researchers measured how much facial acne lesions decreased over 12 weeks compared to a placebo. The goal is t…

This study tested whether a new tablet called VHX-896 works the same as the standard drug iloperidone in 26 adults with schizophrenia or bipolar I disorder. Participants took both versions at different times to compare drug levels in the blood and check for side effects. The goal…

This study tested a drug called imsidolimab in 8 adults with generalized pustular psoriasis (GPP), a rare and severe skin condition. The drug is an antibody that targets inflammation. Researchers measured how well it worked using skin scores and other health markers. The goal was…

This phase 2 trial tested a monthly injection called imsidolimab (ANB019) in 59 adults with palmoplantar pustulosis, a chronic skin condition causing painful, pus-filled blisters on the palms and soles. The study compared the drug to a placebo to see if it could reduce the severi…

This study tested whether tradipitant, an oral capsule, can reduce nausea and vomiting in healthy overweight or obese volunteers who also received a GLP-1 receptor agonist (a class of weight-loss drugs). 124 participants were randomly assigned to tradipitant or a placebo. The mai…

This phase 2 trial tested whether VSJ-110 eye drops can reduce itching and redness caused by allergic conjunctivitis (eye allergies). 47 adults received either the active eye drop or a placebo, then were exposed to an allergen. The study measured how much their eyes itched and re…