New eye drop shows promise for allergy itch

NCT ID NCT04622345

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This phase 2 trial tested whether VSJ-110 eye drops can reduce itching and redness caused by allergic conjunctivitis (eye allergies). 47 adults received either the active eye drop or a placebo, then were exposed to an allergen. The study measured how much their eyes itched and reddened in the minutes after exposure. Results will show if VSJ-110 works better than placebo for quick symptom relief.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
VSJ-110 ophthalmic solution (eye drops)
What this could lead to
If it works, this could lead to a new eye drop that quickly relieves itching and redness caused by eye allergies.
What could go wrong
This is a small, early-phase trial (47 people) testing a short-term response in a lab setting. Real-world effectiveness and long-term safety are unknown.

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Conditions

The condition(s) this trial relates to.

atopic conjunctivitis Conjunctivitis, Allergic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vanda Investigational Site

    Andover, Massachusetts, 01810, United States

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