Experimental drug trichostatin a tested for safety in tough blood cancers

NCT ID NCT03838926

Recruiting now Disease control Sponsor: Vanda Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study is testing whether a drug called trichostatin A is safe for people with blood cancers that have returned or not responded to standard treatments. About 42 adults will receive the drug through an IV to find the highest safe dose and watch for side effects. The goal is not to cure the cancer but to see if the drug can be tolerated and studied further.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: trichostatin A
What this could lead to: If successful, this could identify a safe dose of trichostatin A for further testing in blood cancer patients.
What could go wrong: This is a very early Phase 1 trial with only 42 participants, focused on safety, not effectiveness. The drug may not work against the cancer or could cause serious side effects.

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Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid system neoplasm neoplasm Recurrence refractory hematologic cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RELAPSED OR REFRACTORY HEMATOLOGIC MALIGNANCIES

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Vanda Investigational Site
WITHDRAWN

Washington D.C., District of Columbia, 20007, United States
Vanda Investigational Site
COMPLETED

Lafayette, Indiana, 47905, United States
Vanda Investigational Site
WITHDRAWN

Hackensack, New Jersey, 07601, United States
Vanda Investigational Site
COMPLETED

Seattle, Washington, 98109, United States
Vanda Investigational Site
RECRUITING

Biała Podlaska, Poland

Contact Phone: •••-•••-••••
Vanda Investigational Site
RECRUITING

Katowice, Poland

Contact Phone: •••-•••-••••
Vanda Investigational Site
COMPLETED

Krakow, Poland
Vanda Investigational Site
RECRUITING

Opole, Poland

Contact Phone: •••-•••-••••
Vanda Investigational Site
COMPLETED

Skorzewo, Poland
Vanda Investigational Site
RECRUITING

Warsaw, Poland

Contact Phone: •••-•••-••••
Vanda Investigational Site
COMPLETED

Wroclaw, Poland

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