Habitual spontaneous abortion

This study tested whether a combination of intravenous immunoglobulin (IVIg) and prednisolone can increase the chance of a live birth in women who have had two or more unexplained miscarriages after fertility treatments like IVF. Eighty women were randomly assigned to receive eit…

This early trial tested whether low doses of interleukin-2 (IL-2) could boost regulatory T cells in women who had at least five unexplained miscarriages. The goal was to see if this immune-calming approach could eventually prevent the body from rejecting a pregnancy. Only 18 wome…

This study looked at 363 women with a history of three or more miscarriages who carry a specific gene mutation (MTHFR C677T). Researchers compared two treatments during pregnancy: aspirin plus folic acid, or the same plus a blood thinner (enoxaparin). The goal was to see which ap…

This study looked at how the brain and heart respond to stressful images and sounds in women who have had multiple pregnancy losses and also have anxiety. Researchers used special head sensors and heart monitors to measure these reactions in 70 women. The goal was to find pattern…

This study aimed to find new reasons why some women have repeated miscarriages with no known cause. Researchers looked at specific genetic markers (microRNA 410 and BIRC7) in 86 women aged 20-30 who had two or three miscarriages. The goal was to better understand the disease, not…

This study looked at whether sperm DNA damage is linked to early recurrent pregnancy loss in couples where standard tests found no cause. Researchers compared sperm samples from men in couples with unexplained recurrent pregnancy loss to those from men who had a healthy pregnancy…

This completed study looked at whether the types of bacteria in a woman's gut are linked to having repeated miscarriages. Researchers compared stool and blood samples from 60 women with a history of two or three miscarriages to those with complication-free pregnancies. The goal w…

This pilot study examines whether cells from a woman’s firstborn son or older brother can be found in her blood and if they are linked to recurrent pregnancy loss. Researchers will take blood and cheek swab samples from 32 women who have had at least three miscarriages. The goal …