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Could gut bugs play a role in repeated miscarriages?

NCT ID NCT07246486

Knowledge-focused Sponsor: Dr. Natascha Köstlin-Gille Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at whether the types of bacteria in a woman's gut are linked to having repeated miscarriages. Researchers compared stool and blood samples from 60 women with a history of two or three miscarriages to those with complication-free pregnancies. The goal was to see if differences in gut microbiome composition, hormone levels, or bacterial byproducts might help explain recurrent pregnancy loss. No treatment was given; this was purely an observational study to gather knowledge.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Nov 2020

Finished

Feb 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

non-pregnant women between 18 and 40 years

Ages

18 to 40 years

Sex

Female participants only

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient of the fertility center of the university hospital Tübingen * 2 or 3 spontaneous abortions in medical history Exclusion Criteria: * Age under 18 years, age over 40 years * Current pregnancy * Immunosuppressive therapy * Antibiotic therapy up to four weeks before admission * Acute infection * Orale intake of probiotics up to four weeks before admission

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Conditions

The condition(s) this trial relates to.

Abortion, Spontaneous habitual spontaneous abortion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spontaneous abortion

Contacts and locations

Locations

  • University Hospital Tübingen

    Tübingen, Baden-Wurttemberg, 72076, Germany

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