Habitual spontaneous abortion

This early-phase study tests whether a woman's own natural killer cells, processed in a lab and infused into her uterus, can improve uterine immune function and lead to successful pregnancy. It includes 14 women with a history of recurrent miscarriage, failed IVF, unexplained inf…

This study tests whether a brain-training technique called neurofeedback can help reduce anxiety in women who have had repeated pregnancy losses. Participants use a headband that monitors brain activity and plays a calming sound when the brain is in a relaxed state. The trial com…

This study is looking at whether women with lower ovarian reserve (fewer eggs) have had more early miscarriages in the past. Researchers will measure ovarian reserve with a blood test (AMH) and an ultrasound (antral follicle count) in over 2,000 women seeking fertility care. This…

This study is looking at whether immune system imbalances contribute to repeated IVF failure or unexplained miscarriages. Researchers will collect blood samples from 150 women (including healthy controls) to measure immune cell types and inflammatory markers. The goal is to ident…

This study looks at whether a single session of a brain stimulation technique called rTMS can change heart activity in women who have had multiple pregnancy losses and also have anxiety. Forty-six women will receive either real or fake stimulation while their heart rate is monito…

This study explores whether a non-invasive brain stimulation technique called rTMS can change heart activity in women who have had multiple pregnancy losses and also suffer from anxiety. Fifty-five women will receive six different intensities of stimulation while their heart rate…

This study is looking at the gum health and mouth bacteria of 30 women who have had three or more miscarriages. Researchers want to see if there is a connection between certain bacteria in the mouth and pregnancy loss. Participants will have a standard dental checkup and provide …

This study aims to find genetic factors that may cause repeated miscarriages or unexplained fetal deaths. Researchers will collect biological samples from 200 couples who have experienced at least three early miscarriages or a fetal death in the second or third trimester. By comp…

This study looks at immune cells in the womb lining and blood of women with unexplained infertility or repeated miscarriages, compared to fertile women. Researchers want to see if differences in these cells help explain why some women have trouble getting pregnant. The study invo…

This study looks at how common post-traumatic stress disorder (PTSD) symptoms are in women who have had a miscarriage in the first three months of pregnancy. Researchers will use questionnaires to measure symptoms and recovery stages. The goal is to better identify women who coul…

This study follows 700 women who have had three or more early miscarriages or repeated implantation failures. Researchers will collect medical history, run tests, and track outcomes to find immune and genetic factors that may cause these losses. The goal is to better understand w…

This study looks at whether low levels of a protein called mannose-binding lectin (MBL) in the blood are linked to repeated pregnancy loss or failed IVF attempts. Researchers will measure MBL levels in 500 women with these conditions and compare them to the general population. Th…

This study looks at the bacteria living in the vagina and womb of women who have had two or more miscarriages. Researchers want to see if these bacterial communities differ from those in fertile women. The goal is to understand if the microbiome plays a role in recurrent pregnanc…