Sperm DNA damage may play role in unexplained miscarriages
NCT ID NCT02572154
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether sperm DNA damage is linked to early recurrent pregnancy loss in couples where standard tests found no cause. Researchers compared sperm samples from men in couples with unexplained recurrent pregnancy loss to those from men who had a healthy pregnancy. The goal was to see if higher sperm DNA fragmentation is more common in the miscarriage group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If this study finds a link, it could point toward new ways to evaluate male fertility in couples with recurrent pregnancy loss.
What could go wrong
This is a small, completed observational study, not a treatment trial. It may not prove cause and effect, and results may not apply to all couples.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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APHM
Marseille, France
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Chu Bordeaux
Bordeaux, France
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Chu Toulouse
Toulouse, France