Could immune drugs help prevent miscarriages after IVF? new trial results awaited.

NCT ID NCT04701034

Completed Disease control Sponsor: Aalborg University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a combination of intravenous immunoglobulin (IVIg) and prednisolone can increase the chance of a live birth in women who have had two or more unexplained miscarriages after fertility treatments like IVF. Eighty women were randomly assigned to receive either the active drugs or a placebo during early pregnancy. The goal was to see if calming the immune system could help more pregnancies survive past the first trimester.

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Conditions

The condition(s) this trial relates to.

Abortion, Spontaneous habitual spontaneous abortion infertility disorder pregnancy loss, recurrent, 4 pregnancy loss, recurrent, susceptibility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FERTILITY DISORDERS HABITUAL ABORTION MISCARRIAGE RECURRENT PREGNANCY LOSS

Contacts and locations

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Locations

• The Centre for Recurrent Pregnancy Loss of Western Denmark, Department of Obstetrics and Gynaecology, Aalborg University Hospital

Aalborg, 9000, Denmark