Can aspirin and blood thinners prevent recurrent miscarriages?
NCT ID NCT05864937
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 363 women with a history of three or more miscarriages who carry a specific gene mutation (MTHFR C677T). Researchers compared two treatments during pregnancy: aspirin plus folic acid, or the same plus a blood thinner (enoxaparin). The goal was to see which approach better prevented another miscarriage. The study was retrospective, meaning it looked back at past medical records.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- aspirin, folic acid, and enoxaparin (a blood thinner)
- What this could lead to
- If effective, this combination could help prevent recurrent miscarriages in women with this specific gene mutation.
- What could go wrong
- This is a retrospective study, not a randomized trial, so results may be less reliable. The benefit of adding enoxaparin is uncertain and carries bleeding risks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Amiens-Picardie
Amiens, 80054, France
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