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Ear infection
MONDO:0021666A viral or bacterial infection that affects the external, middle, or inner ear. It may follow an upper respiratory infection. Signs and symptoms include pain, ear discharge, ear fullness, hearing loss, vertigo, nausea, and vomiting.
Also known as: Ear infection, otitis
72 clinical trials for this condition and its sub-types.
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Broader categories
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New ear oil shows promise against fungal infections
⭐️ CURE ⭐️ CompletedThis study tested whether miconazole oil can cure fungal ear infections (otomycosis). 112 adults with ear fungus received either the active oil or a placebo for 14 days. Neither patients nor doctors knew who got the real treatment. After two weeks, doctors checked if the infectio…
Phase: PHASE3 • Sponsor: Hill Dermaceuticals, Inc. • Aim: ⭐️ CURE ⭐️
Last updated Jun 27, 2026 12:31 UTC
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New vaccine shows promise against childhood ear infections
⭐️ VACCINE ⭐️ CompletedThis study tested a new vaccine called V114 in over 7,000 healthy infants to see if it could prevent ear infections caused by certain pneumococcal bacteria. The vaccine was given alongside routine childhood shots. Researchers tracked how many babies got vaccine-type ear infection…
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 08:12 UTC
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New pneumonia vaccine passes first safety check in small human trial
⭐️ VACCINE ⭐️ CompletedThis early-stage trial tested whether a new whole-cell pneumonia vaccine is safe for people. Thirty healthy adults received either the vaccine or a placebo and were monitored for 30 days. The main goal was to check for side effects like pain, fever, or headache. This study does n…
Phase: PHASE1 • Sponsor: Serum Life Science Europe GmbH • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 07:55 UTC
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Molecular map may guide treatment for mysterious inflammatory illnesses
Disease control CompletedThis study tested whether analyzing a patient's DNA and RNA could help doctors pick the right drug for inflammatory diseases that don't fit standard categories. 32 adults with at least two affected organs (including skin) received one of six targeted therapies based on their mole…
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Ear drop showdown: which works better for fungal infections?
Disease control CompletedThis study compared two ear drop treatments for otomycosis, a fungal infection of the outer ear that causes itching, discharge, and blockage. Sixty patients were randomly assigned to receive either clotrimazole or 2% salicylic acid drops three times daily for two weeks. The main …
Phase: NA • Sponsor: Mayo Hospital Lahore • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Ear infection showdown: boric acid vs. povidone iodine
Disease control CompletedThis study tested two common treatments for fungal ear infections: boric acid and povidone iodine. Sixty patients were treated with one of the two solutions applied directly to the ear canal. The goal was to see which one clears the infection better and reduces symptoms like pain…
Phase: NA • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Rural patients get Hospital-Level care at home in landmark trial
Disease control CompletedThis study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New rapid test for infection and inflammation put to the test
Diagnosis CompletedThis study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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New PET tracer aims to light up hidden infections
Diagnosis CompletedThis early study tested a new radioactive tracer called 18F-FDS in 16 people with suspected bacterial or fungal infections. The tracer is designed to light up infection sites on PET/CT scans, helping doctors see exactly where an infection is. The goal was to check how the tracer …
Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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New PET scan technique aims to sniff out hidden infections
Diagnosis CompletedThis early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…
Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Beetroot jelly could give swimmers a natural edge
Symptom relief CompletedThis study investigates whether a beetroot powder jelly candy can help competitive swimmers swim faster and feel less tired. Beetroot is rich in nitrate, which the body converts to nitric oxide, a compound that may improve blood flow and muscle efficiency. The trial involves 21 s…
Phase: NA • Sponsor: Halic University • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Ear spray showdown: can ectoin soothe outer ear itch?
Symptom relief CompletedThis study looked at two ear sprays—Ectoin Ear Spray and Normison Ear Spray—to see how well they work and if they are safe for people with chronic itching and skin irritation of the outer ear canal. 60 adults took part in this real-world observation. The main goal was to check if…
Sponsor: Bitop AG • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Study explores how family and friends impact caregiver health
Knowledge-focused CompletedThis completed study looked at how the social networks of caregivers affect their stress and health when caring for someone with an inherited disease. Researchers surveyed over 680 participants, including family members and formal caregivers, to understand caregiving burden and s…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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PET scans outshine older method for rare ear infection?
Knowledge-focused CompletedThis study compared two imaging methods—PET/CT and labeled leukocyte scintigraphy—for monitoring malignant otitis externa, a serious infection of the ear canal that can spread to the skull. Researchers looked at 18 patients who had both scans before and after antibiotic treatment…
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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ICU antibiotic dosing: what really matters?
Knowledge-focused CompletedThis study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Smart reports guide doctors to better antibiotic choices
Knowledge-focused CompletedThis study tested whether giving doctors automated reports on their antibiotic prescribing habits could improve how often they follow official guidelines. Researchers looked at over 26,000 patients with pneumonia, ear infections, or sore throat. They compared antibiotic use befor…
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC