New vaccine shows promise against childhood ear infections
NCT ID NCT04193215
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new vaccine called V114 in over 7,000 healthy infants to see if it could prevent ear infections caused by certain pneumococcal bacteria. The vaccine was given alongside routine childhood shots. Researchers tracked how many babies got vaccine-type ear infections and monitored for serious side effects. The goal was to see if V114 works better than no V114 at preventing these infections.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
V114 (Pneumococcal 15-Valent Conjugate Vaccine)
What this could lead to
If successful, this vaccine could reduce the number of ear infections caused by certain pneumococcal bacteria in young children.
What could go wrong
This is a completed phase 3 trial, but results may not apply to all children or regions. Ear infections can still be caused by other germs not covered by the vaccine.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Bamrasnaradura Infectious Disease Institute ( Site 0011)
Nonthaburi, 11000, Thailand
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Bhumibol Adulyadej Hospital ( Site 0013)
Sai Mai, Bangkok, 10220, Thailand
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Chiang Rai Prachanuchro Hospital-Pediatrics ( Site 0015)
Chiang Rai, 57000, Thailand
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Chulalongkorn University ( Site 0008)
Bangkok, Bangkok, 10330, Thailand
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Faculty of Medicine Thammasat Univ. ( Site 0007)
Khong Luang, Changwat Pathum Thani, 12120, Thailand
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Maharaj Nakorn Chiang Mai Hospital ( Site 0001)
Chiang Mai, 50200, Thailand
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Panyananthaphikkhu Chonprathan Medical Center ( Site 0014)
Pak Kret, Changwat Nonthaburi, 11120, Thailand
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Phramongkutklao Hospital ( Site 0003)
Bangkok, Bangkok, 10400, Thailand
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Prince of Songkla University Faculty of Medicine ( Site 0005)
Hat Yai, Changwat Songkhla, 90110, Thailand
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Ramathibodi Hospital, Mahidol University ( Site 0009)
Rajthevee, Bangkok, 10400, Thailand
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Sappasit Prasong Hosptial-Pediatric ( Site 0016)
Ubon Ratchathani, 34000, Thailand
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Siriraj Hospital ( Site 0004)
Bangkok, Bangkok, 10700, Thailand
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Srinagarind Hospital ( Site 0002)
Khon Kaen, 40002, Thailand