Disease
MONDO:0000001A disease is a disposition to undergo pathological processes that exists in an organism because of one or more disorders in that organism.
Also known as: condition, disease, disease or disorder, disease or disorder, non-neoplastic, diseases, diseases and disorders, disorder, disorders
106141 clinical trials for this condition and its sub-types, 738 tagged with Disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Disease
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Human disease 15 trials · 106,065 incl. sub-types
4 sub-types
- Disease by body system or component 0 trials · 94,022 incl. sub-types Sub-types →
- Disease by etiologic mechanism 0 trials · 60,180 incl. sub-types Sub-types →
- Disease by developmental or physiological process 0 trials · 36,262 incl. sub-types Sub-types →
- Acute disease 23 trials · 4,756 incl. sub-types Sub-types →
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Non-human animal disease 0 trials · 48 incl. sub-types
55 sub-types
- Integumentary system disorder, non-human animal 0 trials · 15 incl. sub-types Sub-types →
- Hereditary disease, non-human animal 0 trials · 9 incl. sub-types Sub-types →
- Metabolic disease, non-human animal 0 trials · 9 incl. sub-types Sub-types →
- Sheep disease 0 trials · 9 incl. sub-types Sub-types →
- Infectious disease, non-human animal 0 trials · 7 incl. sub-types Sub-types →
- Cattle disease 0 trials · 6 incl. sub-types Sub-types →
- Nervous system disorder, non-human animal 0 trials · 6 incl. sub-types Sub-types →
- Inflammatory disease, non-human animal 0 trials · 5 incl. sub-types Sub-types →
- Nutritional disorder, non-human animal 0 trials · 5 incl. sub-types Sub-types →
- Digestive system disorder, non-human animal 0 trials · 4 incl. sub-types Sub-types →
- Goat disease 0 trials · 4 incl. sub-types Sub-types →
- Cancer or benign tumor, non-human animal 0 trials · 3 incl. sub-types Sub-types →
- Disorder of visual system, non-human animal 0 trials · 3 incl. sub-types Sub-types →
- Endocrine system disorder, non-human animal 0 trials · 3 incl. sub-types Sub-types →
- Swine disease 0 trials · 3 incl. sub-types Sub-types →
- Disorder of orbital region, non-human animal 0 trials · 2 incl. sub-types Sub-types →
- Dog disease 0 trials · 2 incl. sub-types Sub-types →
- Auditory system disorder, non-human animal 0 trials · 1 incl. sub-types Sub-types →
- Fish disease 0 trials · 1 incl. sub-types Sub-types →
- Musculoskeletal system disorder, non-human animal 0 trials · 1 incl. sub-types Sub-types →
- Non-human primate disease 0 trials · 1 incl. sub-types Sub-types →
- Acute disease, non-human animal 0 trials Sub-types →
- Bird disease 0 trials Sub-types →
- Cardiovascular disorder, non-human animal 0 trials Sub-types →
- Cat disease 0 trials Sub-types →
- Chromosomal disorder, non-human animal 0 trials Sub-types →
- Connective tissue disorder, non-human animal 0 trials Sub-types →
- Disease related to transplantation, non-human animal 0 trials
- Disorder of development or morphogenesis, non-human animal 0 trials Sub-types →
- Disorder of glycosylation, non-human animal 0 trials Sub-types →
- Hematologic disorder, non-human animal 0 trials Sub-types →
- Horse disease 0 trials Sub-types →
- Iatrogenic disease, non-human animal 0 trials Sub-types →
- Idiopathic disease, non-human animal 0 trials Sub-types →
- Immune system disorder, non-human animal 0 trials Sub-types →
- Lameness, non-human animal 0 trials
- Mammary gland disorder, non-human animal 0 trials Sub-types →
- Mitochondrial disease, non-human animal 0 trials Sub-types →
- Mouth disorder, non-human animal 0 trials Sub-types →
- Narcolepsy, non-human animal 0 trials Sub-types →
- Obstetric disorder, non-human animal 0 trials Sub-types →
- Occupational disorder, non-human animal 0 trials
- Otorhinolaryngologic disease, non-human animal 0 trials Sub-types →
- Perinatal disease, non-human animal 0 trials
- Poisoning, non-human animal 0 trials
- Post-infectious disorder, non-human animal 0 trials Sub-types →
- Premature aging syndrome, non-human animal 0 trials Sub-types →
- Psychiatric disorder, non-human animal 0 trials Sub-types →
- Radiation-induced disorder, non-human animal 0 trials
- Reproductive system disorder, non-human animal 0 trials Sub-types →
- Respiratory system disorder, non-human animal 0 trials Sub-types →
- Rodent disease 0 trials Sub-types →
- Syndromic disease, non-human animal 0 trials Sub-types →
- Ulcer disease, non-human animal 0 trials Sub-types →
- Urinary system disorder, non-human animal 0 trials Sub-types →
Most studied deeper sub-types
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Sickle cell transplant study halted after just one patient
Disease control Stopped earlyThis study tested a drug called siplizumab alongside a stem cell transplant for people with severe sickle cell disease. The goal was to see if it could prevent the body from rejecting the new cells and reduce a serious side effect called graft-versus-host disease. Only one person…
Phase 1/2 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Can a drug combo let HIV patients ditch daily meds?
Disease control Stopped earlyThis study tested two experimental drugs, budigalimab and ABBV-382, in people with HIV who were stable on standard therapy. Participants stopped their usual HIV medications to see if the new drugs could keep the virus under control. The trial was terminated early, so it's unclear…
Phase 2 • Sponsor: AbbVie • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Tears may replace spinal taps for MS diagnosis
Diagnosis Stopped earlyThis study tests whether a tear sample can diagnose primary progressive multiple sclerosis (MS) as accurately as a spinal tap. Currently, doctors need to collect spinal fluid to confirm this type of MS, which is invasive and uncomfortable. Researchers will compare proteins in tea…
Sponsor: Lille Catholic University • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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New scan spots hidden thyroid cancer better?
Diagnosis Stopped earlyThis study tested a new type of PET scan (called 68Ga-MY6349) that targets a protein called Trop-2 on cancer cells. It was used in 149 adults with thyroid cancer to see if it could find cancer that had come back or spread. The results were compared to the standard FDG-PET scan to…
Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Diagnosis
Last updated Jun 27, 2026 12:39 UTC
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New blood test aims to cut unnecessary colonoscopies after cancer screen
Diagnosis Stopped earlyThis pilot study tested a blood-based test (Harbinger test) to help decide who needs a colonoscopy after a positive colorectal cancer screening. The goal was to see if the blood test could accurately predict colorectal cancer or advanced adenomas. However, the study was terminate…
Sponsor: Harbinger Health • Aim: Diagnosis
Last updated Jun 27, 2026 12:06 UTC
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Ultrasound may replace MRI for Kids' ankle injuries
Diagnosis Stopped earlyThis study looked at whether ultrasound can accurately diagnose ankle injuries in children aged 5 to 17. Researchers compared ultrasound results to MRI, which is considered the gold standard. The goal was to see if ultrasound could be a faster, radiation-free way to diagnose inju…
Sponsor: University Hospital, Lille • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC
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New device measures skin stiffness to track lymphedema
Knowledge-focused Stopped earlyThis study tested a device called a durometer that measures skin elasticity in people with lymphedema. The goal was to see if the device could help track disease progression. Only 7 people took part, and the study was stopped early.
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC