Degenerative myopia
MONDO:0001383Excessive axial myopia associated with complications (especially posterior staphyloma and choroidal neovascularization) that can lead to blindness.
Also known as: progressive high (degenerative) myopia
50 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Could special contact lenses slow worsening eyesight in young adults?
Disease control ENROLLING_BY_INVITATIONThis study tests whether dual focus contact lenses (MiSight) can slow the progression of nearsightedness (myopia) in university students aged 18 to 21. Participants wear either the test lenses or standard single vision lenses for at least 10 hours a day. Researchers measure chang…
Phase: NA • Sponsor: University of Bradford • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Eye drops may halt worsening nearsightedness in adults
Disease control OngoingThis study tests whether eye pressure-lowering medication can slow the progression of severe nearsightedness (high myopia) in adults. Researchers will measure changes in eye length and vision over time. The trial includes 152 participants aged 18 to 65 with worsening high myopia …
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Eye-Opening study: amino acids may slow nearsightedness in young adults
Disease control OngoingThis study tests whether taking branched-chain amino acid (BCAA) supplements for six months can slow the progression of myopia (nearsightedness) in young adults aged 18 to 25. Participants either receive BCAA supplements plus standard glasses or a placebo plus glasses. The goal i…
Phase: NA • Sponsor: Zhongda Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New lenses aim to slow Kids' nearsightedness
Disease control OngoingThis study tests whether special new spectacle lenses can slow the worsening of nearsightedness (myopia) in children. About 342 kids aged 7 to 13 will wear either the new lenses or standard single-vision glasses for one year, then all switch to the new lenses for another year. Th…
Phase: NA • Sponsor: Shanghai Eye Disease Prevention and Treatment Center • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Gas-Free eye surgery could revolutionize macular hole repair
Disease control OngoingThis study tests a new surgical technique to close macular holes in people with high myopia without using a gas bubble. The standard approach requires a gas bubble that blurs vision and forces patients to keep their head down for days. The new method uses a gel-like substance to …
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New glasses lens could slow Kids' nearsightedness
Disease control OngoingThis study tests whether a special lens called Blue Star MAX-5 can slow the progression of nearsightedness (myopia) in children aged 8 to 11. Two hundred kids will wear either the new lens or standard glasses and be checked every six months for two years. The goal is to see if th…
Phase: NA • Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New glasses aim to halt adult nearsightedness
Disease control OngoingThis study tests whether Essilor Stellest spectacle lenses can slow the progression of nearsightedness (myopia) in adults aged 18 to 40. Each participant wears a Stellest lens in one eye and a standard lens in the other, allowing direct comparison. The trial measures changes in e…
Phase: NA • Sponsor: University of Ulster • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New eye drops could help kids see clearly longer
Disease control OngoingThis study tests a new eye drop called SHJ002 to see if it can safely slow down worsening nearsightedness (myopia) in children ages 3 to 12. The drop works by targeting a specific molecule in the eye. Researchers will compare it to a standard treatment, atropine, and measure chan…
Phase: PHASE2 • Sponsor: Sunhawk Vision Biotech, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New lens design aims to halt worsening eyesight in children
Disease control ENROLLING_BY_INVITATIONThis study tests special 3D-designed defocus lenses to see if they can slow down myopia (nearsightedness) in children aged 6 to 14. The lenses are meant to control how the eye grows, reducing the need for stronger glasses over time. Researchers will track changes in vision and ey…
Phase: NA • Sponsor: Shanghai Eye Disease Prevention and Treatment Center • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New glasses could slow kids' worsening eyesight
Disease control OngoingThis study tests whether special open-ring spectacle lenses can slow the progression of nearsightedness (myopia) in Chinese children aged 6 to 12. A total of 180 children will wear one of three lens designs for 12 months, with some continuing for another year. The goal is to see …
Phase: NA • Sponsor: Shanghai Eye Disease Prevention and Treatment Center • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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New glasses design may help stop Kids' eyesight from getting worse
Disease control OngoingThis study tests whether special glasses with a double helix lens design can slow the progression of myopia (nearsightedness) in children and adolescents aged 6 to 13. About 236 participants will wear either the new glasses or standard single-vision glasses for over 10 hours a da…
Phase: NA • Sponsor: Shanghai Eye Disease Prevention and Treatment Center • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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AI eye test: could a computer replace your eye doctor?
Diagnosis ENROLLING_BY_INVITATIONThis study compares a new AI system, called AEYE, against a human eye doctor in diagnosing keratoconus and deciding who is eligible for laser vision correction. The AI analyzes patient history, eye scans, and other data to make its recommendations. Researchers will check if the A…
Sponsor: Hazem Yassin Clinics • Aim: Diagnosis
Last updated Jun 26, 2026 17:00 UTC
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Special lens may slow nearsightedness – tiny study looks at how
Knowledge-focused OngoingThis study looks at how a new type of eyeglass lens affects the back layer of the eye (the choroid) in children with worsening nearsightedness. Ten children already in a larger study will have their eye thickness measured with a special camera. The goal is to understand if the le…
Phase: NA • Sponsor: SightGlass Vision, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Free eye tests aim to catch vision loss early in harlem and washington heights
Knowledge-focused OngoingThis study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC