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Degenerative myopia
MONDO:0001383Excessive axial myopia associated with complications (especially posterior staphyloma and choroidal neovascularization) that can lead to blindness.
Also known as: progressive high (degenerative) myopia
50 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New study tests extra treatments for kids whose nearsightedness keeps getting worse despite special lenses
Disease control Not yet recruitingThis study will enroll about 3,890 children aged 8-12 who still have rapidly worsening nearsightedness (myopia) even after using orthokeratology (Ortho-K) lenses. Researchers will compare four approaches: continuing Ortho-K alone, adding low-dose atropine eye drops, using lenses …
Sponsor: Tianjin Medical University Eye Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Smart glasses aim to stop Kids' eyesight from getting worse
Disease control Not yet recruitingThis study tests special glasses called D.D.C dual-control lenses to see if they can slow down worsening nearsightedness (myopia) in children aged 6 to 14. Over 24 months, 316 kids will wear either the new lenses or standard glasses. The goal is to measure changes in eye prescrip…
Phase: NA • Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Can red light stop severe nearsightedness from worsening in adults?
Disease control Not yet recruitingThis study tests if low-intensity red light therapy can slow or stop the worsening of high and extreme myopia (severe nearsightedness) in adults aged 18 to 45. The treatment has shown promise in children, but its effects in adults are unknown. The goal is to prevent vision loss a…
Phase: NA • Sponsor: Beijing Tongren Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Red light therapy tested to stop Kids' eyesight from worsening
Disease control Not yet recruitingThis study tests if using a special LED red light device twice a day, along with glasses that have defocus lenses, can slow the progression of nearsightedness (myopia) in children aged 6 to 14. About 364 kids will be randomly assigned to different groups to find the best treatmen…
Phase: NA • Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New lens technique aims to reduce glasses dependency after cataract surgery
Disease control Not yet recruitingThis trial tests whether an enhanced monofocal intraocular lens, set for monovision (one eye for distance, one for near), improves vision without glasses in people with both cataracts and high myopia. Sixty-six participants will receive the lens in both eyes and be followed for o…
Phase: NA • Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Disease control
Last updated Jun 26, 2026 17:33 UTC
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AI eye doctor: new study aims to spot Blindness-Causing diseases faster
Diagnosis Not yet recruitingThis study will test a new artificial intelligence (AI) system that reads eye scans (OCT) to diagnose common blinding eye diseases like diabetic retinopathy, glaucoma, and age-related macular degeneration. Researchers will collect 2000 eye scans from patients at Peking Union Medi…
Sponsor: Peking Union Medical College Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 07:59 UTC
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AI vs. human eye: study tests if smart software improves retinal reports
Knowledge-focused Not yet recruitingThis study looks at whether giving eye doctors AI-generated measurements from retinal images helps them write more accurate and complete reports. About 29 ophthalmologists and trainees will be randomly assigned to use AI tools or just the original images. A panel of senior expert…
Sponsor: Beijing Tongren Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC