Degenerative myopia

This study will enroll about 3,890 children aged 8-12 who still have rapidly worsening nearsightedness (myopia) even after using orthokeratology (Ortho-K) lenses. Researchers will compare four approaches: continuing Ortho-K alone, adding low-dose atropine eye drops, using lenses …

This study tests if low-intensity red light therapy can slow or stop the worsening of high and extreme myopia (severe nearsightedness) in adults aged 18 to 45. The treatment has shown promise in children, but its effects in adults are unknown. The goal is to prevent vision loss a…

This study tests if using a special LED red light device twice a day, along with glasses that have defocus lenses, can slow the progression of nearsightedness (myopia) in children aged 6 to 14. About 364 kids will be randomly assigned to different groups to find the best treatmen…

This trial tests whether an enhanced monofocal intraocular lens, set for monovision (one eye for distance, one for near), improves vision without glasses in people with both cataracts and high myopia. Sixty-six participants will receive the lens in both eyes and be followed for o…

This study will test a new artificial intelligence (AI) system that reads eye scans (OCT) to diagnose common blinding eye diseases like diabetic retinopathy, glaucoma, and age-related macular degeneration. Researchers will collect 2000 eye scans from patients at Peking Union Medi…

This trial compares pain relief from bandage contact lenses soaked in the anti-inflammatory drug ketorolac versus plain lenses after photorefractive keratectomy (PRK), a type of laser eye surgery. PRK often causes significant pain in the first few days as the cornea heals. The st…

This study follows 1,000 preschool children (ages 0-6) with refractive errors like nearsightedness, farsightedness, or astigmatism. Researchers aim to map how these conditions progress, identify related health issues, and find the best ways to correct vision early. The goal is to…

This study looks at whether giving eye doctors AI-generated measurements from retinal images helps them write more accurate and complete reports. About 29 ophthalmologists and trainees will be randomly assigned to use AI tools or just the original images. A panel of senior expert…