Degenerative myopia
MONDO:0001383Excessive axial myopia associated with complications (especially posterior staphyloma and choroidal neovascularization) that can lead to blindness.
Also known as: progressive high (degenerative) myopia
50 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Eye drops could keep Kids' vision from getting worse
Disease control CompletedThis study tested three low doses of atropine eye drops (0.01%, 0.03%, and 0.05%) in 95 children aged 6–18 with nearsightedness. The goal was to see which dose best slowed the worsening of myopia with the fewest side effects. Over 18 months, the 0.05% dose worked best at controll…
Phase: PHASE3 • Sponsor: Khyber Medical College, Peshawar • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New drug faricimab takes on leading cause of blindness in nearsighted people
Disease control CompletedThis study tested a drug called faricimab (VABYSMO®) against an existing treatment (ranibizumab) for people with vision loss caused by abnormal blood vessels growing in the back of the eye due to severe nearsightedness. The trial involved 280 participants who received either fari…
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Can bifocals plus eye drops beat drops alone for Kids' nearsightedness?
Disease control CompletedThis study looked at whether adding bifocal glasses to daily atropine eye drops works better than atropine alone to slow down nearsightedness (myopia) in children. 210 kids aged 4-16 with worsening myopia took part. The main goal was to measure changes in their vision prescriptio…
Phase: NA • Sponsor: University of Faisalabad • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Laser tweak to eye implants could sharpen sight without extra surgery
Disease control CompletedThis study tested a special laser (femtosecond laser) to adjust an artificial lens already placed inside the eye after cataract surgery. The goal was to correct leftover blurriness or astigmatism so people need glasses less. Twelve adults with at least one diopter of remaining re…
Phase: NA • Sponsor: Perfect Lens, LLC • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Can a nightly eye drop tame severe nearsightedness in kids?
Disease control CompletedThis study tested three strengths of atropine eye drops (0.01%, 0.04%, and 0.1%) in 219 children with high myopia (severe nearsightedness). The goal was to see which dose best slows the worsening of vision and eye growth over two years. Children received one drop in each eye ever…
Phase: NA • Sponsor: Shanghai Eye Disease Prevention and Treatment Center • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New combo therapy may slow severe nearsightedness in kids
Disease control CompletedThis study tested whether combining low-dose atropine eye drops with special soft contact lenses can slow the progression of high myopia (severe nearsightedness) in children aged 6-12. 120 children were split into three groups: one got the combo therapy, one got atropine alone wi…
Phase: PHASE4 • Sponsor: Beijing Tongren Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New light field device could revolutionize eye exams
Diagnosis CompletedThis study tested a new prototype device that uses light field technology to measure vision problems like nearsightedness and farsightedness. Researchers compared its accuracy to standard methods in 120 healthy adults. The goal was to see if this new approach could reliably deter…
Sponsor: Daniela Nosch • Aim: Diagnosis
Last updated Jun 26, 2026 14:12 UTC
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Could eye pigment levels predict vision damage in severe nearsightedness?
Knowledge-focused CompletedThis study examined 39 people with severe nearsightedness to see if lower levels of a natural eye pigment (macular pigment) are linked to tiny cracks in the back of the eye called lacquer cracks. These cracks can lead to vision loss. The researchers measured the pigment's optical…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Can your phone replace an eye exam? new study puts app to the test
Knowledge-focused CompletedThis study checked if a smartphone app called VisionApp can accurately measure vision problems like nearsightedness and presbyopia (age-related reading difficulty). Sixteen adults aged 40 and older used the app at home, and their results were compared to standard eye exams. The g…
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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New eye device docking tested in 55 adults
Knowledge-focused CompletedThis study tested how well a new device (ELITA) docks onto the eye for refractive error treatment. 55 adults participated to see if the docking procedure works correctly. The study did not provide treatment, only measured the device's performance.
Sponsor: Johnson & Johnson Surgical Vision, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC