Chronic bronchitis
MONDO:0005607A type of chronic obstructive pulmonary disease characterized by chronic inflammation in the bronchial tree that results in edema, mucus production, obstruction, and reduced airflow to and from the lung alveoli. The most common cause is tobacco smoking. Signs and symptoms include coughing with excessive mucus production, and shortness of breath.
Also known as: bronchitis, chronic
35 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New COPD drug shows promise in cutting lung Flare-Ups
Disease control OngoingThis study tests a new drug called verekitug in 666 people with moderate-to-severe COPD, a long-term lung disease that makes breathing hard. The goal is to see if it can reduce serious flare-ups and improve lung function compared to a placebo. Participants must be current or form…
Phase: PHASE2 • Sponsor: Upstream Bio Inc. • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Simple breathing workout speeds recovery after lung transplant
Symptom relief OngoingThis study tests whether using a breathing muscle training device, along with standard physical therapy, helps people recover more quickly after a lung transplant. About 90 adults waiting for a lung transplant will take part. The goal is to see if this training improves breathing…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Tiny study hopes to Fine-Tune breathing machines for lung patients
Knowledge-focused OngoingThis study looks at how changing the pressure inside a breathing machine affects lung function in 20 patients with obstructive airway diseases who are on full ventilator support. Researchers will test different pressure levels to see how they impact gas exchange and how the lungs…
Phase: NA • Sponsor: Hospital Donación Francisco Santojanni • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Massive italian study aims to uncover what really affects COPD survival
Knowledge-focused ENROLLING_BY_INVITATIONThis large real-world study will follow 10,000 Italian patients with COPD to see how their treatments, flare-ups, and other health conditions affect their risk of death. Researchers will collect data on medications, lung function, and heart problems over time. The goal is to bett…
Sponsor: University of Milan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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New breathing test could detect hidden lung disease
Knowledge-focused OngoingThis study is testing whether a breathing test called the lung clearance index (LCI) can detect small airways disease in adults with chronic lung conditions like asthma or fibrosis. Researchers will compare results from 300 patients with lung disease to 300 healthy volunteers. Th…
Sponsor: National Jewish Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Massive COPD study aims to unlock secrets of lung disease
Knowledge-focused OngoingThis study follows nearly 3,000 people with COPD (a chronic lung disease) over several years to understand how the disease progresses and what factors influence it. Researchers measure lung function, analyze mucus, and track environmental exposures like air pollution. The goal is…
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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COPDGene: unlocking the genetic secrets of lung disease in smokers
Knowledge-focused OngoingThis study is looking at over 10,000 smokers to find out if certain genes make some people more likely to develop COPD, a serious long-term lung disease. Participants are having their lung function tested and getting chest CT scans. The goal is to understand why some smokers get …
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:03 UTC