New breathing test could detect hidden lung disease
NCT ID NCT03241420
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether a breathing test called the lung clearance index (LCI) can detect small airways disease in adults with chronic lung conditions like asthma or fibrosis. Researchers will compare results from 300 patients with lung disease to 300 healthy volunteers. The goal is to see if LCI is a reliable, noninvasive marker for early lung injury.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could provide a simple, noninvasive way to detect early lung damage in chronic lung diseases.
- What could go wrong
- This is an observational study, not a treatment trial. The LCI technique may not prove sensitive enough to replace current tests.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Jewish Health
Denver, Colorado, 80206, United States
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