Chronic bronchitis

This phase 2 trial tests whether galvokimig, an experimental biologic drug, can reduce the number of moderate-to-severe COPD flare-ups in people with chronic bronchitis. About 400 adults aged 40 to 80 with moderate-to-severe COPD will receive either galvokimig or a placebo as an …

This study is testing whether giving air conditioners and a $100 electricity subsidy to older adults in Boston neighborhoods can reduce heat stress, heat strain, and related health problems. One hundred participants aged 55-95 who don't have AC will be randomly assigned to receiv…

This study looks at whether people with COPD and chronic bronchitis who switch from regular cigarettes to a tobacco heating system feel better and breathe easier. About 290 adults aged 40 and older who have smoked for at least 10 years will take part. Researchers will measure cou…

This study looks at whether Street Racket, a simple racket sport, can be added to standard pulmonary rehabilitation for people with chronic lung disease. Twelve participants will play Street Racket every two weeks during their rehab program. Researchers will measure how acceptabl…

This study compares two COPD self-management education programs: a self-guided booklet and a counselor-led phone program. Researchers want to see which approach better reduces hospitalizations and improves quality of life. 448 adults with COPD who have been hospitalized in the pa…

This study tests a device that delivers gentle electric pulses to the airways to reduce chronic bronchitis symptoms in adults with COPD. About 210 participants will either receive the real treatment or a sham procedure. The goal is to see if the treatment improves breathing and q…

This study looks at how the relationship between doctors and patients affects the way medical decisions are made. Researchers will interview 300 patients and healthcare workers in Singapore to understand what makes a good partnership. The goal is to learn how these partnerships c…

This study looks at the physical properties of lung mucus in people with obstructive pulmonary disease. Researchers will collect sputum samples before and after chest physiotherapy or exercise to see how these treatments change the mucus. The goal is to better understand the dise…

This study aims to find the genes that make some people develop severe COPD at a young age, even if they smoke. Researchers will collect DNA and health information from 2,000 participants with early-onset COPD. The goal is to understand why some people are more prone to this lung…

This study is creating a registry of people with emphysema to collect DNA, lung function tests, and medical information. Researchers hope to use this data to better understand the disease and develop new therapies. The registry will also help identify volunteers for future resear…