Cure My Disease

Don't miss your cure!

 Log in / Sign up

COPDGene: unlocking the genetic secrets of lung disease in smokers

NCT ID NCT00608764

Ongoing Knowledge-focused Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is looking at over 10,000 smokers to find out if certain genes make some people more likely to develop COPD, a serious long-term lung disease. Participants are having their lung function tested and getting chest CT scans. The goal is to understand why some smokers get COPD and others don't, which could lead to better ways to predict and prevent the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help identify people at high risk for COPD and guide future prevention or treatment strategies.
What could go wrong
This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results may take years to apply in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BRONCHITIS, CHRONIC are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

chronic bronchitis chronic obstructive pulmonary disease COPD, severe early onset pulmonary emphysema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHITIS, CHRONIC EMPHYSEMA PULMONARY DISEASE, CHRONIC OBSTRUCTIVE

Contacts and locations

Locations

  • Ann Arbor VA Medical Center

    Ann Arbor, Michigan, 48105, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • HealthPartners Research Foundation

    Minneapolis, Minnesota, 55440, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21224, United States

  • Los Angeles Biomedical Research Institute

    Torrance, California, 90502, United States

  • Minneapolis VA Medical Center

    Minneapolis, Minnesota, 55417, United States

  • Morehouse School of Medicine

    Atlanta, Georgia, 30310, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • Reliant Medical Group

    Worcester, Massachusetts, 01608, United States

  • Temple University

    Philadelphia, Pennsylvania, 19140, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35249, United States

  • University of California at San Diego

    San Diego, California, 92103, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Texas Health Sciences Center at San Antonio

    San Antonio, Texas, 78229, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.