COPDGene: unlocking the genetic secrets of lung disease in smokers
NCT ID NCT00608764
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is looking at over 10,000 smokers to find out if certain genes make some people more likely to develop COPD, a serious long-term lung disease. Participants are having their lung function tested and getting chest CT scans. The goal is to understand why some smokers get COPD and others don't, which could lead to better ways to predict and prevent the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify people at high risk for COPD and guide future prevention or treatment strategies.
What could go wrong
This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results may take years to apply in practice.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ann Arbor VA Medical Center
Ann Arbor, Michigan, 48105, United States
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Columbia University Medical Center
New York, New York, 10032, United States
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Duke University
Durham, North Carolina, 27710, United States
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HealthPartners Research Foundation
Minneapolis, Minnesota, 55440, United States
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Johns Hopkins University
Baltimore, Maryland, 21224, United States
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Los Angeles Biomedical Research Institute
Torrance, California, 90502, United States
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Minneapolis VA Medical Center
Minneapolis, Minnesota, 55417, United States
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Morehouse School of Medicine
Atlanta, Georgia, 30310, United States
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National Jewish Health
Denver, Colorado, 80206, United States
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Reliant Medical Group
Worcester, Massachusetts, 01608, United States
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Temple University
Philadelphia, Pennsylvania, 19140, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35249, United States
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University of California at San Diego
San Diego, California, 92103, United States
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University of Iowa
Iowa City, Iowa, 52242, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15232, United States
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University of Texas Health Sciences Center at San Antonio
San Antonio, Texas, 78229, United States