Chorioamnionitis
MONDO:0000409A morphologic finding indicating inflammation of the fetal sac membranes. It is characterized by neutrophilic infiltration of the amnion and chorion.
Also known as: fetal membrane inflammation, foetal membrane inflammation, inflammation of fetal membrane, inflammation of foetal membrane, intra-amniotic infection
10 clinical trials for this condition and its sub-types.
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Can a saline flush during labor shield newborn brains?
Disease control Not yet recruitingThis study tests whether infusing fluid into the uterus during labor (amnioinfusion) can reduce brain injury in newborns whose mothers have a uterine infection called chorioamnionitis. The infection can cause inflammation and fever that may stress the baby's brain before birth. R…
Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Could a Two-Antibiotic cocktail prevent infections after water breaks?
Disease control Not yet recruitingThis study looks at whether giving two antibiotics (ampicillin and gentamicin) instead of one (ampicillin alone) can better prevent infections in pregnant women whose water breaks before labor starts. About 320 women at term will be randomly assigned to one of the two treatments.…
Phase 4 • Sponsor: Sarawak General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Superbug risk in preterm pregnancy: new study seeks answers
Knowledge-focused Not yet recruitingThis study looks at how often pregnant women who have their water break early carry antibiotic-resistant bacteria. Researchers will collect samples from 250 women across French hospitals to track these bacteria and identify risk factors. The goal is to help doctors choose better …
Sponsor: Centre Hospitalier de Saint-Denis • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC