Childhood onset asthma

This study tests whether text-message reminders and coaching can help 389 teens (ages 12-18) with moderate to severe asthma take their daily inhaled steroids as prescribed. Participants will be split into three groups: one gets a basic asthma app, another adds personalized text r…

This study tests a family-empowered pulmonary rehabilitation program for school-age children (6-12 years) with asthma. The program includes education, skills training, and home-based guidance. Researchers will compare it to standard care in 92 children to see if it improves asthm…

The ROOT study is testing a personalized nutrition program for pregnant women. Participants receive standard prenatal care plus customized diet and lifestyle plans based on their genes and nutrient levels. The goal is to see if this approach can lower the chances of preterm birth…

This study tests a program where children with asthma take their daily medicine at school, supervised by staff. The goal is to see if this helps more children take their medicine correctly and reduces asthma attacks. The trial will include 300 children in Rochester, New York, and…

This study tests a digital health assistant called 'Alex' to help children and teens aged 10 to 19 with asthma. Over six months, the app tracks lung function, symptoms, and medication use, and later gives personalized advice. The goal is to see if it improves asthma control and m…

This study tests whether giving children a single inhaler for both daily control and quick symptom relief at school can reduce asthma attacks and emergency visits. About 330 children aged 6–12 with moderate-to-severe asthma will take part across Rochester City schools. School nur…

This study tests a computer program that scans electronic medical records to help family doctors find asthma in children aged 2 to 5. The goal is to catch the disease earlier, which could reduce serious breathing problems and deaths. About 300 children from four clinics in France…

This study will follow over 200,000 infants in France to see if early immunization with nirsevimab, an antibody against RSV, reduces wheezing episodes in preschool years. Researchers will compare hospitalization rates for wheezing between immunized and non-immunized children. The…

This study tests whether adding exercise sessions and asthma education to usual care helps children aged 10-17 manage their asthma better. 60 participants will be randomly placed into one of three groups: usual care only, education only, or exercise plus education. The goal is to…

This study tests whether wearing a special LED vest for 20 minutes twice a week can improve lung function and exercise ability in children aged 6 to 17 with mild to moderate asthma. The vest uses light to reduce inflammation without heat. Half the children will get the active ves…

This study tests whether giving children aged 5-17 with severe asthma attacks early breathing support (called BPAP) in the emergency room is practical and safe. About 36 children will either get standard asthma care alone or standard care plus BPAP. The goal is to see if this app…

This study looks at whether watching cartoons or listening to breath-synchronized interactive stories can help children aged 6-9 feel less afraid and more comfortable while using a nebulizer for breathing medication. About 96 children with respiratory conditions will be randomly …

This study tests if applying cold (cryotherapy) to the wrist before a blood draw from the artery can reduce pain. It involves 258 adults with chronic respiratory diseases who need this test. The goal is to find a simple, drug-free way to make the procedure less painful.

This study looks at how to get all pediatric clinics and hospitals in the Basque Health Service to use a proven care plan for children with asthma attacks. About 4,680 children will be involved. The goal is to see which strategies work best to make sure every child gets the right…

This study follows 270 preterm babies (born before 32 weeks) from birth to age 3. Researchers will regularly swab their noses to analyze the bacteria and other microbes living there. The goal is to see if the nose microbiome can predict which babies will develop bronchopulmonary …

This study tests a mobile app called ALRITE that helps health workers in Uganda diagnose and manage breathing illnesses in young children. The app guides them through patient information and gives treatment recommendations. Researchers will see if using the app improves how often…

This study will test whether a brief educational session led by a nurse can help children aged 6-17 with asthma better manage their condition and use their inhaler correctly. The session covers understanding treatment, distinguishing between maintenance and rescue medications, an…

This observational study will analyze samples from 160 children with asthma, protracted bacterial bronchitis, or chronic cough to find biomarkers that predict disease progression and treatment response. Participants will undergo a bronchoscopy to collect lung fluid and tissue sam…