Childhood disintegrative disorder

This study will enroll 1,000 adults with both opioid use disorder and a mental health condition. Participants will receive standard medication for opioid use disorder, with some also getting a team-based support program called MISSION. The goal is to see if MISSION helps people s…

This study tests a program called Tunawiri (meaning 'thrive') that adds mental health screening, counseling, and support to regular HIV care for pregnant and postpartum women in Kenya. The goal is to improve depression, anxiety, and HIV treatment success. Nine hundred women will …

This study tests a gamified mobile health app designed to reduce suicide risk in adults with mental disorders after they leave the hospital. Researchers will enroll 640 participants in Shenzhen, China, and use game-like features to encourage treatment adherence and follow-up visi…

This study tests whether a non-invasive brain stimulation technique called TMS can help people with mental illness quit smoking. Forty daily smokers with psychiatric conditions will receive either TMS or standard care. The goal is to see if TMS is practical and effective in real-…

This study tests a program called SKILLS that focuses on common factors across different mental health conditions, rather than treating each disorder separately. About 60 adults with stable psychiatric diagnoses will take part. The goal is to see if this approach reduces symptoms…

This study tests a program called SUPERCEDE, which provides intensive case management to veterans who are at risk for suicide and receive care both from the VA and outside community providers. The goal is to improve care coordination, reduce suicidal thoughts, and improve daily f…

This pilot study tests whether adding ear acupressure (small seeds taped to ear points) to standard nicotine patches or gum can reduce cravings, withdrawal symptoms, and anxiety in psychiatric inpatients who must stop smoking during their hospital stay. Sixty participants will be…

This study is testing whether a virtual reality version of a therapy exercise is practical and helpful for adults (ages 18-65) with psychiatric disorders. Participants will try one VR session and answer questions about their experience. The goal is to see if this approach is acce…

This study tests an AI chatbot called Aurora that guides people through creating a personal life story to improve emotional well-being and identity. It includes healthy adults, adults with mental health conditions in residential care, and older adults aged 65+. The chatbot is not…

This study is testing a type of talk therapy called Emotion Regulation Therapy (ERT) delivered over video for people in New York who struggle with worry, overthinking, or being hard on themselves. The goal is to see if the therapy helps people better manage their emotions and fee…

This study tests whether a team of a psychologist, speech therapist, and motor therapist can help children aged 2-7 with neurodevelopmental disorders eat more foods and have fewer mealtime struggles. 24 children will be split into two groups: one gets the team therapy, the other …

This study looks at how well and how safely a new sleep medication, lemborexant, works for people who have both a mental health condition and trouble sleeping. About 121 adults will take the drug for 8 weeks, and researchers will track changes in their sleep quality and any side …

This study looks at whether watching Netflix or Disney shows in a small group for 90 minutes each week, over 6 weeks, can improve emotional awareness and reduce anxiety and depression. About 70 adults who have been in mental health treatment for at least 6 months will take part. …

This study tests a multi-sensory therapy called Heal, which uses calming sounds, gentle vibrations, and soft lighting to help detained youth (ages 12-18) manage their emotions before counseling sessions. The goal is to see if this brief, non-verbal intervention improves emotional…

This study tests whether sailing can help people with psychiatric disorders feel better. Forty adults in France will either take sailing lessons or continue their usual care. Researchers will measure changes in quality of life, mental well-being, and self-esteem to see if sailing…

This study tests a new approach called ENGAGE, where children with disabilities (like autism or cerebral palsy) help set their own therapy goals. About 96 kids aged 5-12 and their therapists will be split into two groups: one using ENGAGE and the other using usual therapy. Resear…

This study tests whether a speech therapy that involves parents can improve early social and communication skills in children aged 6 months to 5 years with neurodevelopmental disabilities. One group gets the parent-focused therapy, while the other gets standard speech therapy. Re…

This study follows 450 babies born with serious heart defects to find early signs of developmental delays by 6 months of age. Researchers want to understand why over half of these children face learning, thinking, or behavior challenges later in life. The goal is to identify risk…

This study aims to learn more about childhood-onset behavioral, psychiatric, and developmental disorders by observing people of all ages who have these conditions, along with their family members. Researchers will collect medical histories, perform psychiatric assessments, and ma…

This study compares two ways to help adults with mental health issues get follow-up care. One group gets usual care after an emergency room visit, while the other uses a new system that books a psychiatrist appointment within 48 hours through their general doctor. Researchers wil…

This study looks at how the brain responds to sensory inputs like sight and sound in 200 children and adults, some with neurodevelopmental disorders (NDD) and some without. Participants will have EEG recordings during sensory tasks, complete behavioral tests, and practice percept…

This study looks at whether a tool called the Decision Helper helps people with mental health conditions take a more active role in choosing their treatment. About 62 adults in Danish outpatient mental health clinics will have their consultations recorded and analyzed. The goal i…

This study looks at the mental health of 200 teenagers aged 12 to 16 who attend special educational institutes (ITEPs) in France. Researchers will use psychiatric interviews to find out how many have conditions like depression or anxiety. The goal is to better understand their ne…

This study aims to learn how sleep changes as children's brains grow, by collecting sleep and development data from healthy children and those with conditions like autism or ADHD. About 244 children ages 6 months to 8 years will have overnight sleep studies, developmental tests, …

This study aims to improve suicide prevention for people who move between healthcare and the criminal-legal system. Researchers will link health records, Medicaid data, and jail booking information to identify individuals at risk and coordinate care. Over 1,000 adults with past p…

This study looks at medical records of 1000 children with conditions like autism, epilepsy, and Down syndrome to find common biological patterns. Researchers want to understand what causes these disorders and how children respond to treatments. The goal is to improve diagnosis an…

This study looks at ways to help families show up for their scheduled appointments at clinics for autism and other neurodevelopmental disorders. Researchers will test different types of reminder messages and see if having a patient navigator call high-risk families makes a differ…

This study looks at whether a program with a nurse case manager can help people leaving prison visit a doctor or clinic instead of the emergency room. About 488 adults with a history of substance use and a chronic health condition will take part. Some will get extra support from …

This study observes 100 people with rare genetic neurodevelopmental disorders like Baker Gordon Syndrome and Syt-1 disorder. Researchers will track symptoms, collect genetic and imaging data, and create cell models to better understand these conditions. The goal is to improve dia…

This study looks at whether a recovery-focused program can help people with severe mental illness living in supported housing. About 72 participants will either receive the new program or standard care. The goal is to see if focusing on personal goals improves daily functioning a…

This study follows 1,000 people who have certain genetic changes (hnRNP and others) that may cause developmental delays, autism, seizures, or muscle problems. Researchers collect medical records, school reports, and questionnaires to see how these gene variants affect behavior, t…

This study is creating a program called START-VET to help veterans with mental illness or substance use disorders who have recently left prison. Researchers will work with 20 veterans to develop transition materials and tools. The goal is to improve quality of life and reduce cri…

This observational study follows 300 adults receiving strategic psychotherapy—a short-term, goal-focused talk therapy—in private practice. Participants fill out questionnaires about their symptoms and well-being before and after treatment. The goal is to see if this therapy leads…

This study tests whether a child-focused goal-setting method called ENGAGE helps children with neurodevelopmental disabilities do better in therapy. About 96 kids aged 5-12 and their therapists will be split into two groups: one using ENGAGE and one using usual care. Researchers …

This pilot study is testing whether a simple saliva test can help doctors prescribe mental health medications more safely and effectively. 200 adults in Manitoba who are starting or changing psychiatric drugs will provide a DNA sample. The results will be shared with their doctor…

This study looks at whether training psychiatric care teams to talk about sexual health with young patients (ages 15 and up) increases those conversations. Researchers will survey 770 teens hospitalized for psychiatric disorders about their sexual health and any side effects from…