Calcinosis
MONDO:0002123Deposition of calcium in the tissues. It may be the result of a metabolic disorder or long-standing infection, or it may be associated with the presence of cancer.
Also known as: calcification, calcium deposit(s), deposit(s), calcium, macrocalcification, pathologic calcification, pathologically calcified structure
48 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
Dialysis fluid shows promise in slowing artery hardening
Disease control CompletedThis study looked at whether adding citrate to the fluid used during dialysis can slow the buildup of calcium in blood vessels. 54 adults on hemodialysis who already had some vessel hardening took part. Each person used a standard fluid for 12 months and a citrate fluid for anoth…
Phase: NA • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
-
New Shockwave-Stent combo tackles tough leg artery blockages
Disease control CompletedThis completed study tested a two-step treatment for severely calcified leg artery disease in 50 patients. First, a shockwave device cracks the hard calcium deposits, then a drug-coated stent is placed to keep the artery open. The goal was to see if this approach is safe and effe…
Sponsor: Marc Bosiers, MD • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
-
Diabetes drug shows promise for kidney and heart health in Non-Diabetic patients
Disease control CompletedThis study tested whether dapagliflozin, a drug typically used for diabetes, can slow kidney decline, improve anemia, and support heart health in 100 adults with chronic kidney disease who do not have diabetes. Participants took either the drug or a placebo daily for 12 months al…
Phase: PHASE3 • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
-
New Imaging-Guided biopsy aims to improve breast cancer detection
Diagnosis CompletedThis study tested whether using contrast-enhanced mammography to guide breast biopsies is more accurate than the standard X-ray-guided method for suspicious calcifications. About 184 women with suspicious calcifications (BIRADS R3-R5) were randomly assigned to one of the two biop…
Phase: NA • Sponsor: Azienda USL Reggio Emilia - IRCCS • Aim: Diagnosis
Last updated Jun 27, 2026 12:31 UTC
-
Probiotic shows promise in preventing menopause bone loss
Prevention CompletedThis study tested whether taking a probiotic called Lactobacillus acidophilus can help prevent bone loss and osteoporosis in women after menopause. 90 women aged 45-70 with a BMI between 27 and 35 took either the probiotic or a placebo. Researchers measured calcium levels and bon…
Phase: NA • Sponsor: Poznan University of Life Sciences • Aim: Prevention
Last updated Jun 27, 2026 08:09 UTC
-
Rare, deadly skin condition under the microscope: french study sheds light on calciphylaxis
Knowledge-focused CompletedThis study looked back at 80 French patients with calciphylaxis, a rare and often fatal condition causing painful skin ulcers, mostly in people with severe kidney disease. Researchers aimed to describe patient characteristics, how doctors diagnose and treat the condition, and wha…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
-
Common blood thinners may speed up artery calcification, study suggests
Knowledge-focused CompletedThis study looked at whether vitamin K antagonists (a type of blood thinner) are linked to more calcium buildup in the aorta, the body's main artery. Researchers compared 73 patients—some on the drug for at least 6 months and some who never took it—using CT scans. The goal was to…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
-
CT scan score may predict dangerous leaks after colon surgery
Knowledge-focused CompletedThis study looked at whether a simple score based on artery calcifications seen on a CT scan can help predict a serious complication called anastomotic leakage after right colon removal. Over 600 adults scheduled for surgery had their CT scans reviewed. The goal is to see if a hi…
Sponsor: Centre Hospitalier Departemental Vendee • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
-
AI boosts chest X-Ray reading in UK hospital study
Knowledge-focused CompletedThis study tested whether an AI tool called Lunit INSIGHT CXR helps healthcare professionals read chest X-rays more accurately and quickly. Thirty doctors and radiographers reviewed 500 past chest X-rays from two UK hospitals, once with and once without AI help. The goal was to s…
Sponsor: Oxford University Hospitals NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
-
Study reveals HPV vaccine gaps in teens with chronic illness
Knowledge-focused CompletedThis study looked at how many girls and young women aged 11 to 20 with chronic diseases (like diabetes or immune conditions) got the HPV vaccine, compared to those without chronic illness. Researchers reviewed records of 223 participants from a hospital in France. The goal was to…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC