New Shockwave-Stent combo tackles tough leg artery blockages

NCT ID NCT05291247

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested a two-step treatment for severely calcified leg artery disease in 50 patients. First, a shockwave device cracks the hard calcium deposits, then a drug-coated stent is placed to keep the artery open. The goal was to see if this approach is safe and effective at maintaining blood flow for 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Shockwave intravascular lithotripsy device and a drug-eluting vascular stent

What this could lead to

If successful, this combination could offer a safer, more effective way to open severely calcified leg arteries, reducing the need for repeat procedures.

What could go wrong

This is a small, completed trial with 50 participants, so results may not apply to everyone. The procedure carries risks like vessel rupture, blood clots, or heart complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PERIPHERAL ARTERIAL DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

calcinosis peripheral arterial disease Vascular Calcification

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Klinikum Hochsauerland

    Arnsberg, North Rhine-Westphalia, 59759, Germany

  • SRH Klinikum Karlsbad-Langensteinbach

    Baden-Baden, Baden-Wurttemberg, 76307, Germany

  • St. Marien Hospital Lünen

    Lünen, North Rhine-Westphalia, 44534, Germany

  • University Hospital Eppendorf

    Hamburg, Free and Hanseatic City of Hamburg, 20246, Germany

  • University Hospital Essen

    Essen, North Rhine-Westphalia, 45147, Germany

  • University Hospital LMU Munich

    Munich, Bavaria, 80337, Germany