Can a Diamond-Coated rotating crown unclog calcified heart arteries?

NCT ID NCT05447585

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This trial tests a new atherectomy device that uses a diamond-coated rotating crown to grind away calcium buildup in heart arteries. It aims to see if this device can safely and effectively prepare the artery for stent placement in people with calcified coronary artery disease. The study compares the new device to an existing rotational atherectomy system in about 239 adults aged 18 to 80 who are scheduled for stent implantation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Coronary atherectomy system (a device with a diamond-coated rotating crown to remove calcium from artery walls)
What this could lead to
If successful, this device could offer a safer, more effective way to clear calcified coronary arteries, improving stent placement and reducing heart complications.
What could go wrong
This is an early-stage trial, and the device may not outperform existing atherectomy systems. Risks include procedure-related complications like vessel damage or heart events.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310009, China