Bronchopulmonary dysplasia
MONDO:0019091Bronchopulmonary dysplasia is a chronic respiratory disease that results from complications related to lung injury during the treatment of infant acute respiratory distress syndrome in low-birth-weight premature infants or from abnormal lung development in older infants. Clinical signs are tachypnea, tachycardia and signs of respiratory distress such as intercostal recession, grunting and nasal flaring.
Also known as: BPD
90 clinical trials for this condition and its sub-types.
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Abandoned study: can a common painkiller help close a tiny heart vessel in preemies?
Disease control TerminatedThis study tested whether adding acetaminophen to standard ibuprofen treatment could better close a blood vessel (ductus arteriosus) that stays open too long in very premature infants. The trial was planned for preterm babies born at or before 27 weeks and 6 days who needed breat…
Phase: PHASE2 • Sponsor: University of South Alabama • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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New breathing mode tested in tiny infants with severe lung condition
Symptom relief TerminatedThis study tested two different ways of using a breathing machine (ventilator) in 12 premature infants with severe bronchopulmonary dysplasia (BPD), a serious lung condition. One mode, called NAVA, uses the baby's own diaphragm signals to trigger breaths, while the other, CMV, us…
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Musical pacifier may help preemies with lung disease eat sooner
Symptom relief TerminatedThis study tested a special pacifier that plays music or a mother's voice when a baby sucks correctly. It aimed to help premature infants with chronic lung disease learn to feed by mouth more quickly. The trial enrolled 33 babies but was stopped early, so the results are not conc…
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC