Alopecia areata

This study tested special clothing made with Lumiton yarn that captures sunlight and turns it into red and near-infrared light, aiming to improve skin conditions like psoriasis, alopecia areata, and polymorphous light eruption. Eighteen adults with mild-to-severe forms of these c…

This study tested baricitinib, an anti-inflammatory pill, in 784 adults with severe or very severe alopecia areata, a condition causing extensive hair loss. Participants received either baricitinib or a placebo for up to 52 weeks. The main goal was to see if baricitinib could reg…

This study tested a drug called PF-06651600 in over 1,000 adults and teenagers with alopecia areata, a condition that causes patchy or complete hair loss. The goal was to see if the drug is safe and helps hair grow back over the long term. A smaller group also checked how well th…

This study tested the drug baricitinib in 606 adults with severe or very severe alopecia areata, a condition causing significant hair loss. Participants took either baricitinib or a placebo pill daily for up to 36 weeks. The main goal was to see if baricitinib could regrow enough…

This Phase 3 trial tested whether low doses of interleukin-2 (IL2) can help people with severe alopecia areata, a condition causing patchy or total hair loss. 44 adults with at least 50% scalp hair loss who had not responded to other treatments received either IL2 injections or a…

This early-stage trial tested a drug called IMG-007 in 29 adults with alopecia areata who had lost at least half of their scalp hair. The main goal was to check safety, but researchers also measured hair regrowth using a standard tool. The study is now complete, and results will …

This study tested whether tofacitinib, a drug already approved for arthritis, is safe and helpful for immune-related skin conditions in people with Down syndrome. 47 adolescents and adults with Down syndrome and skin issues like eczema or psoriasis took the drug. Researchers chec…

This study tested the long-term safety and effectiveness of a drug called CTP-543 in 407 adults with moderate to severe alopecia areata, a condition that causes patchy or complete hair loss. Participants had already completed 24 weeks of treatment in a previous trial. The goal wa…

This completed trial tested whether an oral anti-inflammatory drug called roflumilast can regrow hair as well as steroid injections in people with mild-to-moderate patchy alopecia areata. Fifty adults with limited to moderate hair loss were enrolled. The main goal was to measure …

This study looked at 20 adults with severe alopecia areata (hair loss) to see how the drug baricitinib changes certain immune markers in the blood. Researchers measured levels of two proteins, interleukin-15 and interferon gamma, before and after six months of treatment. The goal…

This study analyzed data from a database to understand how adults with severe alopecia areata and their doctors experienced treatment with ritlecitinib compared to older treatments. Researchers looked at patient characteristics, treatment history, and doctor satisfaction. The goa…

This study looked at 39 people with immune-related hair loss affecting at least half their scalp. Researchers collected blood, skin samples, and swabs to study genes, immune signals, and skin microbes. The goal was to better understand what causes alopecia, not to test a treatmen…

This study examined whether a specific change in the TLR7 gene is more common in people with alopecia areata, an autoimmune condition that causes hair loss. Researchers compared 120 participants (patients and healthy volunteers) to see if the gene variant is linked to the disease…

This study looked at whether a specific gene (NR3C1) that helps control inflammation is linked to alopecia areata, an autoimmune condition that causes hair loss. Researchers compared 120 people with and without the condition to see if gene variations affect disease risk or severi…

This study looked at whether specially engineered versions of a natural immune protein (IL-2) can selectively boost regulatory T cells, which help calm the immune system. Researchers took blood samples from 67 people with various autoimmune or inflammatory conditions and tested t…