Acute necrotizing pancreatitis

This study tests whether taking pancreatic enzyme pills can help people who have lost significant weight after a severe bout of pancreatitis regain a healthier body weight. The trial will enroll 188 adults aged 18-60 who have lost at least 10% of their body weight due to the dise…

This study tests a new blood test that combines genetic sequencing and immune response analysis to quickly tell if dead pancreatic tissue has become infected. Researchers will enroll 200 patients with severe pancreatitis across four hospitals. If accurate, this test could help do…

This study tests whether a thoracic epidural block—a numbing injection near the spine—can help people with severe acute pancreatitis avoid or shorten the need for intensive care support like breathing machines and kidney dialysis. Participants are randomly assigned to receive eit…

This study will review medical records of 700 adults with severe pancreatitis and sepsis who had surgery to remove dead tissue. Researchers want to see how organ function changes over time after the operation. The goal is to better understand recovery patterns and outcomes.