Active tuberculosis
MONDO:0100481Tuberculosis caused by primary infection of or reactivation of latent Mycobacterium tuberculosis. Active tuberculosis characterized by clinical manifestation and active symptoms compatible with tuberculosis, and is distinct from latent tuberculosis infection that occurs without signs or symptoms of active disease.
Also known as: active TB
26 clinical trials for this condition and its sub-types.
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Can a new TB vaccine protect children with HIV?
⭐️ VACCINE ⭐️ TerminatedThis trial is testing two tuberculosis (TB) vaccines—VPM1002 and a repeat BCG vaccination—in pre-adolescents aged 8-14 who were vaccinated at birth. The goal is to see if these vaccines are safe and trigger a strong immune response in children both with and without HIV, and in th…
Phase: PHASE1, PHASE2 • Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group • Aim: ⭐️ VACCINE ⭐️
Last updated Aug 18, 2026 03:00 UTC
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Could a simple blood test revolutionize dormant TB detection?
Diagnosis ENROLLING_BY_INVITATIONThis study evaluates a new blood test that aims to directly detect the bacteria causing dormant tuberculosis (TB), rather than relying on the body's immune response. Current tests cannot tell if treatment worked or who will develop active TB, leading to unnecessary antibiotics. R…
Sponsor: Queen Mary University of London • Aim: Diagnosis
Last updated Jun 27, 2026 09:07 UTC
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Could a One-Month TB pill be as good as three? new trial tests shorter prevention
Prevention OngoingThis study tests whether taking two TB prevention drugs daily for one month works as well as taking them weekly for three months. It includes 1,000 people with HIV or those living with someone recently diagnosed with TB. The goal is to see which schedule more people complete and …
Phase: PHASE4 • Sponsor: The Aurum Institute NPC • Aim: Prevention
Last updated Jun 27, 2026 08:03 UTC
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New study tracks TB drugs in breastmilk to protect infants
Knowledge-focused OngoingThis study looks at how tuberculosis (TB) medications travel through a mother's body, into her breastmilk, and to her nursing baby. Researchers will take blood and milk samples from 20 mothers and small blood samples from their infants at several time points after a dose. The goa…
Sponsor: University of Liverpool • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC