Active tuberculosis

This study looks at how a shorter tuberculosis (TB) treatment regimen works for children and adolescents with non-severe TB in Zambia. It involves children, caregivers, health workers, and policymakers to understand how well the regimen is accepted, followed, and feasible in real…

This study looked at how to best dose two medicines, rifapentine and isoniazid, for children aged 0-12 with latent (hidden) tuberculosis infection. The goal was to find a dose that works as well as in adults to prevent the infection from turning into active TB. The study included…

This study tested a new rapid blood test called SeroSelectTB to see if it can diagnose active tuberculosis (TB) faster than current methods. Over 9,000 adults in South Africa, Tanzania, and Ethiopia who were unwell and suspected of having TB or pneumonia took part. The goal is to…

This study compares two strategies for finding undiagnosed tuberculosis (TB) in peri-urban Uganda. One strategy sets up screening at a large health clinic, while the other sends mobile screening teams into local hotspots where TB is thought to be most common. Researchers will tra…

This study looked at ways to prevent tuberculosis (TB) in Malaysian prisoners, many of whom also had HIV, opioid addiction, or hepatitis. Researchers compared a standard 40-week TB prevention treatment with a shorter 12-week option. The goal was to see which approach worked bette…

This study tested whether people with active tuberculosis can use a smartphone app to send videos of themselves taking their medication, instead of going to a clinic for direct observation. Researchers enrolled 51 patients in Switzerland and measured how many agreed to use the ap…