Active tuberculosis
MONDO:0100481Tuberculosis caused by primary infection of or reactivation of latent Mycobacterium tuberculosis. Active tuberculosis characterized by clinical manifestation and active symptoms compatible with tuberculosis, and is distinct from latent tuberculosis infection that occurs without signs or symptoms of active disease.
Also known as: active TB
26 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New HIV combo pill tested alongside TB treatment in small trial
Disease control Not yet recruitingThis study will compare two different HIV medication combinations in 60 people who also have active tuberculosis. Participants will receive either a newer drug (Ainuovirine) or a standard one (Efavirenz), along with their TB meds. The goal is to see which regimen better suppresse…
Phase: PHASE4 • Sponsor: Shanghai Public Health Clinical Center • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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A mobile x-ray van with AI could spot TB before it spreads
Diagnosis Not yet recruitingThis study tests a community-based screening strategy for tuberculosis (TB) in migrant communities in New York City. A mobile van offers digital chest X-rays with AI interpretation, along with TB symptom checks, blood tests for latent TB, and HIV testing. The goal is to see wheth…
Phase: NA • Sponsor: Columbia University • Aim: Diagnosis
Last updated Aug 01, 2026 00:00 UTC
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Could a tongue swab replace sputum tests for TB?
Diagnosis Not yet recruitingThis large study in five countries will test new, portable diagnostic tools for tuberculosis (TB) that use tongue swabs and AI-assisted chest X-rays. The goal is to see if these faster, easier tests can find more TB cases, especially in people who have no symptoms or can't produc…
Phase: NA • Sponsor: Liverpool School of Tropical Medicine • Aim: Diagnosis
Last updated Jun 27, 2026 12:05 UTC
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AI-Powered skin patch could bring TB prevention to People's doorsteps
Prevention Not yet recruitingThis study explores whether community health workers can use a new skin test, with or without AI help, to test close contacts of TB patients at home instead of at a clinic. The goal is to make it easier for people, especially children and families in Tajikistan and Tanzania, to g…
Phase: NA • Sponsor: KNCV Tuberculosis Foundation • Aim: Prevention
Last updated Jul 22, 2026 00:00 UTC
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Can a smartphone app lift the shame of TB?
Symptom relief Not yet recruitingThis study tests whether online mindfulness, digital cognitive behavioral therapy, and an interactive chatbot can reduce stigma and improve mental health in people with tuberculosis. About 496 adults with active TB will be randomly assigned to receive these digital tools alongsid…
Phase: NA • Sponsor: Peking Union Medical College • Aim: Symptom relief
Last updated Aug 05, 2026 00:00 UTC
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Can immune profiling unlock the hidden stages of tuberculosis?
Knowledge-focused Not yet recruitingThis study aims to better understand tuberculosis (TB) across its entire spectrum—from early, symptom-free infection to active disease and after treatment. Researchers will recruit TB patients and their close contacts to analyze immune responses and identify biomarkers that could…
Sponsor: Irene Latorre Rueda • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Community-Driven TB screening aims to reach vulnerable immigrants
Knowledge-focused Not yet recruitingThis study works with African and South Asian immigrants to design a tuberculosis (TB) screening program that fits their needs. Researchers will hold workshops with immigrants, community leaders, and doctors to identify barriers and create a screening pathway. Then, they will tes…
Sponsor: Universidade Nova de Lisboa • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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AI could revolutionize TB care by predicting who needs shorter treatment
Knowledge-focused Not yet recruitingThis study will use artificial intelligence to analyze data from over 31,000 tuberculosis patients. The goal is to create a system that helps doctors decide which patients can be cured with a short treatment course and which need longer therapy. The AI will be tested to see if it…
Sponsor: Huashan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC