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127005 trials found · Page 6129 of 6351
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New study aims to measure fear of hypoglycemia in french kids with diabetes
Knowledge-focused CompletedType 1 diabetes usually appears brutally in children or young adults. While many factors of poor glycemic balance have been identified in the literature (age, socio-cultural and socio-economic level, family structure, adherence etc.), it turns out that hypoglycemia is the most co…
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Stomach signals may reveal hidden nausea in kids
Knowledge-focused CompletedThe researchers propose to study how functional nausea in adolescents may be characterized noninvasively by the use of multichannel electrogastrogram (EGG) and magnetogastrogram (MGG) recordings.
Early phase 1 • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Scientists scan brains to unlock the mystery of mental and physical tiredness
Knowledge-focused Recruiting nowThe goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and d…
Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Mayo clinic launches lung disease biobank to unlock future treatments
Knowledge-focused Recruiting nowTo develop a repository of blood samples from patients with ILD to support future studies into the development of such biomarkers. Patients with pneumonia and healthy patients will also be recruited as a control group.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Hawaii cancer payment experiment aims to improve care and cut costs
Knowledge-focused OngoingThe HMSA Cancer Episode Payment Model (CEM) is a payment model designed to test the effects of better care coordination on health outcomes and costs of care for Hawaii Medical Services Association (HMSA) members with cancer who receive chemotherapy.
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Sealants tested to keep fillings strong and Stain-Free
Disease control CompletedTreatment clinical trial, randomized, controled, parallel, double-blinded, with three groups, that aims to evaluate if there is some advantage in applying surface sealants (Biscover, Bisco, USA or Permaseal, Ultradent, USA) associated with a Bulk Fill Composite (Tetric N-Ceram Bu…
Sponsor: Universidade Federal Fluminense • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Scientists track what happens to Runners' bodies during Ultra-Trail races
Knowledge-focused CompletedThe practice of mountain running or "trail" is in full development in France and elsewhere in the world. This sporting practice associates specific physiological constraints related in particular to the duration of the efforts made (several hours) and to the ground (important ele…
Sponsor: University Hospital, Grenoble • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Fiber showdown: which type slows digestion the most?
Knowledge-focused CompletedThe digestive process begins in the mouth and follows in the stomach and intestine. In the stomach the food is mixed with the gastric juices forming the chyme. To mix the food with the gastric juice as well as to provide gastric emptying (GE), the movements of the stomach are of …
Sponsor: Federal University of Minas Gerais • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:52 UTC
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New ultrasound tool aims to improve hip replacement precision
Knowledge-focused CompletedProspective, multicenter, non-randomized study. Primary endpoint : to confirm the proper functioning of the device in vivo by analyzing intra and interobserver reproducibility of repeated measurements on healthy controls. Secondary endpoint : to describe the values of pelvic in…
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Music may alter running impact, small study suggests
Knowledge-focused Recruiting nowThe purpose of this study is to determine whether in healthy subjects listening to music while running influences the ground pressure forces, the vertical loading and, overall, the running biomechanics.
Sponsor: Università degli Studi di Sassari • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Healthy volunteers needed to map the Brain's social superpowers
Knowledge-focused Recruiting nowThe goal of this single center non-interventional fMRI and EEG study is to assess the neural bases of social cognitive processing in healthy individuals, and whether/how their responsiveness is modulated by ageing. The main questions it aims to answer are: * are there specific b…
Sponsor: Istituti Clinici Scientifici Maugeri SpA • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Tiny study questions whether math disorder is really a memory problem
Knowledge-focused CompletedResearchers in numerical cognition usually think that the greatest and most common difficulty in children suffering from dyscalculia is retrieval of arithmetic facts from long-term memory. However, we have recently shown that retrieval might not be the optimum strategy in mental …
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Ultrasound vs x-ray: a new way to spot lung issues in sick babies?
Diagnosis Stopped earlyThe diagnosis of bronchiolitis, the most frequent lung infectious disease in infancy, is based on clinical examination. Chest X-ray is proposed when a lung parenchymal condensation is suspected. Chest ultrasound is supposed to be a useful tool in the diagnosis of these complicati…
Sponsor: University Hospital, Toulouse • Aim: Diagnosis
Last updated Jun 27, 2026 13:00 UTC
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Immune cell study sheds light on esophagitis in kids
Knowledge-focused CompletedThe main aim of this study is to assess the expression of innate lymphoid cells in the esophageal mucosa of children with eosinophilic esophagitis (EoE) and in control subjects
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Heart surgery study probes hidden cell stress signals
Knowledge-focused CompletedThe links between systemic inflammation, endothelial dysfunction and endoplasmic reticulum (ER) stress in pre-clinical models make it an interesting potential therapeutic target, but there are no data describing SRE during severe inflammation in humans . For an approach to the s…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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COPD study investigates why patients struggle to fight lung infections
Knowledge-focused Stopped earlyChronic obstructive pulmonary disease (COPD) is a worldwide chronic inflammatory disease of the airways linked to environmental exposure. The chronic course of COPD is often interrupted by acute exacerbations which have a major impact on the morbidity and mortality of COPD patien…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Your phone could help you lose weight: researchers ask for your thoughts
Knowledge-focused Recruiting nowThis study investigates how individuals feel about a dietary mobile application. Information collected from focus groups and interviews may help doctors and mobile application developers to determine preferences and participant feedback about the appeal and usefulness of a mobile…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Scientists zap healthy eyes with lasers to boost diagnostic safety
Knowledge-focused Recruiting nowThe use of lasers in medicine in general, and diagnosis and treatment in ophthalmology in particular, increased significantly. Making retinal surgery using lasers have become increasingly common. The goal: to diagnose eye diseases safely
Sponsor: Sheba Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Heart transplant Patients' health tracked in new registry
Knowledge-focused CompletedThe overall objective of compiling this registry is to obtain a complete collection of data, in a dedicated database, on all patients who have undergone transplantation at our Center in order to assess the main causes of mortality, hospitalization, and morbidity.
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Cervical surgery may alter blood flow to the uterus
Knowledge-focused CompletedThe objective of this prospective study is to evaluate the hemodynamic impact of cervical conization on uterine artery blood flow by focusing on the Resistance Index (RI) as a direct indicator of distal vascular resistance. The central hypothesis is predicated on the physiologica…
Sponsor: Adana City Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC