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116076 trials found · Page 5630 of 5804
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Scientists launch eye tissue bank to unlock secrets of retinal disease
Knowledge-focused Recruiting nowBackground: \- To understand diseases of the retina and the eye, information is needed about people with and without such diseases. Researchers want to study these people and follow them over time. They also want to study body tissues and blood to understand the nature of eye di…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Fine-Tuning MRI scanners to sharpen the picture of the brain
Knowledge-focused CompletedSince January 2010, a new magnetic resonance imaging scanner (Philips 3T, Achieva) is installed on the Baudot Building in Toulouse hospital. This tool, is completely dedicated to the research. It was installed with sequences RMN supplied by the manufacturer. Imagers also contain…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Hidden jaw damage after a child's tooth fracture revealed by 3D scans
Knowledge-focused CompletedThis retrospective study received ethical approval from the Ethics Committee of Dicle University Faculty of Medicine, Diyarbakır, Turkey (Decision No:03.05.2012-567). A priori power analysis (Cohen's d = 0.5, α = 0.05, 80% power) indicated that a minimum of 33 participants was re…
Sponsor: Dicle University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Tummy tuck pain relief: nerve block may cut opioid use
Symptom relief CompletedAbdominoplasty is a major cosmetic surgery with a painful post operative period. Recently more and more anaesthetists are turning to regional analgesia for anterior abdominal wall surgery namely the Transversus Abdominis Plane (TAP) Block with or without ultrasound guidance. The…
Phase: PHASE4 • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Study examines how to better support families of infants with fatal muscle disease
Knowledge-focused CompletedThe purpose of this study is to evaluate the quality of supportive and palliative care for SMA type 1 patients.
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:33 UTC
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Ultrasound showdown: which vein route wins for catheter placement?
Knowledge-focused CompletedThe main objective of this study is to compare the rate of successful establishment of a central venous catheter in the first two attempts of ultrasound-guided puncture between two techniques: (1) a subclavian technique versus (2) an axillary technique.
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Smart monitor may make anesthesia safer during keyhole surgery
Symptom relief CompletedThe Physiodoloris (MetroDoloris, Lille, France) monitor, CE marqued, uses the ECG signal in order to compute the Analgesia Nociception Index (ANI) which has been shown to measure the relative parasympathetic tone, and hence to reflect the analgesia/nociception balance during gene…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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What makes skin cancer patients happy after surgery?
Knowledge-focused CompletedThe primary objective of this study is to measure the overall level of satisfaction in patients after cutaneous surgery in 4 different categories, including the surgeon, facility, procedure and recovery and outcome.
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Are doctors following heart check rules for arthritis patients?
Knowledge-focused CompletedIntroduction Cardiovascular diseases are the first cause of death in rheumatoid arthritis (RA). In 2010, EULAR Standing Committee for Clinical Affairs provides 10 recommendations for cardiovascular risk management in patients with rheumatoid arthritis, including a cardiovascular …
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Epidural drugs may affect Baby's heartbeat, study finds
Knowledge-focused TerminatedThe aim of the investigators study is to demonstrate the association between fetal cardiac rhythm abnormalies after epidural analgesia and the maternal systemic transfer of ropivacaine and/or sufentanil.
Phase: PHASE4 • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Gene study seeks clues to inflammation and disease risk
Knowledge-focused CompletedBackground: \- Research has shown that certain proteins in cells may be linked to higher risks of developing inflammations, tumors, and other medical problems. By examining how the blood cells of healthy volunteers respond to environmental exposures, researchers hope to better u…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Why thigh fat might be better than belly fat: new study
Knowledge-focused CompletedThe purpose of this study is to compare, in healthy women, the adipose tissue composition between abdomen and thigh and then determine whether differences exist independently of the state of obesity. The findings of this study may help to explain the mechanism contributing to a …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:00 UTC
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New scale aims to predict constipation in hospitalized patients
Knowledge-focused CompletedDevelop a risk assessment scale for constipation of hospitalized patients to identify at an early stage high-risk individuals and to implement the appropriate means of prevention.
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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1200 lung biopsies analyzed: how often do complications occur?
Knowledge-focused CompletedAt St. Olavs Hospital, a prospective collection of data on complications related to CT-guided lung biopsies has been conducted over several years as part of quality control study. The primary aim of this quality control study is to map complications in all patients who have under…
Sponsor: St. Olavs Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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1,000 volunteers help scientists unlock secrets of healthy aging
Knowledge-focused CompletedThe purpose of this study is to use the MURDOCK Horizon 1.5 infrastructure (Duke Instutional Review Board Pro00011196) to specifically target and enroll 1,000 participants across age groups and other demographic categories in order to develop a diverse cohort with specific physic…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Gene link to ICU blood sugar problems found
Knowledge-focused CompletedThis study evaluates the link between genetic polymorphisms as r7903146, rs12255372 of TCF7L2 gene and the risk of developing hyperglycemia during Intensive care unit stay
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Power tool for bone marrow biopsies tested in kids
Knowledge-focused CompletedThe purpose of this study is to compare use of a powered bone marrow aspiration and biopsy device (OnControl) to use of a standard manual bone marrow aspiration and biopsy device to obtain bone marrow biopsy specimens in children. The hypothesis is that use of the powered device …
Phase: NA • Sponsor: Vidacare Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New Angle-Measuring tools could make biopsies more accurate
Knowledge-focused CompletedBackground: \- Currently, standard procedures for biopsies that are guided by computed tomography (CT) imaging involve CT scans and a computer program to plan and illustrate where the physician will place the needle to obtain the required cells or tissue. Inserting the biopsy ne…
Phase: PHASE1 • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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New registry tracks mysterious connective tissue disease to uncover clues
Knowledge-focused Recruiting nowThis registry has been established to gain a better understanding of the clinical and emotional presentations of patients with undifferentiated connective tissue disease.
Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Breathing tube removal method may boost oxygen after surgery
Knowledge-focused CompletedThe primary objective is to show that positive pressure extubation improves oxygenation immediately after extubation compared to extubation via "aspiration" by evaluating and comparing the onset time of desaturation during spontaneous ventilation during awakening following genera…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC