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116076 trials found · Page 5497 of 5804
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Shower sooner? new study tests best time to bathe after bone surgery
Knowledge-focused Recruiting nowThis is a single center randomized control trial assessing the effect of early versus delayed bathing on orthopaedic surgical wounds in patients undergoing surgical treatment of fractures. Patients will be recruited by screening all patients undergoing surgical treatment for frac…
Phase: NA • Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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New diabetes drug passes first safety check in healthy men
Knowledge-focused CompletedThis study is testing a new study medicine which may be used to treat people with type 2 diabetes. NNC0650-0013 is a new medicine, which cannot be prescribed by doctors. The purpose of the study is to see if the new study medicine is safe, and how it works in participants body. P…
Phase: PHASE1 • Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Spine adjustments tested for Post-Concussion relief
Knowledge-focused TerminatedThis proof-of-concept trial will explore the effects of manual chiropractic adjustments on nervous system function in individuals with post-concussion syndrome. This study will aim to recruit 10 individuals to receive 6 weeks of chiropractic care with 3 assessment periods. The pa…
Phase: NA • Sponsor: Life University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Sleepless nights may amplify pain, study suggests
Knowledge-focused CompletedThis interventional study aims to test the effects of sleep disruption on pain sensitivity and biomechanics in healthy individuals during experimental knee and shoulder pain. The main question the study aims to answer is: 1\) Does sleep fragmentation increase experimental knee a…
Phase: NA • Sponsor: Aalborg University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Your personality could be key to sticking with CML treatment
Knowledge-focused Recruiting nowThis is an observational pilot study to examine the association between a patient's personality and adherence to tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia.
Sponsor: University of California, Irvine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New dermal filler tested for wrinkle reduction
Symptom relief CompletedThis study designed to evaluate the safety and performance of RefillHA Volume, a dermal filler for facial soft tissue augmentation and correction of facial wrinkles and folds in routine clinical setting.
Sponsor: Glyance • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Tiny study sucks up wound goo to unlock healing secrets
Knowledge-focused CompletedThe observational longitudinal study will collect wound exudate from twenty patients with venous leg ulcers. Wound exudate samples are collected using twenty-four-hour collection with polyurethane foam, bandages and the NovaSwab method. Each patient is seen four times where wound…
Sponsor: Bispebjerg Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New dialysis device for Wilson's disease tested but trial stopped early
Disease control TerminatedThe goal of this clinical trial is to test the MEX-CD1 hemodialysis medical device in patients suffering from Wilson's Disease. The main questions it aims to answer are: * Does the device work as expected by removing the excess of free copper from the blood? * Is the device safe…
Phase: NA • Sponsor: Mexbrain • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Egg study reveals Age-Based differences in HDL and immune response
Knowledge-focused CompletedThe goal of this intervention study is to determine whether consumption of different fractions of chicken eggs, including egg whites, egg yolks, and whole eggs, confer different changes in markers of HDL function and T cell profiles in younger vs. older men and women. The study w…
Phase: NA • Sponsor: University of Connecticut • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Eye imaging showdown: MRI vs ultrasound
Knowledge-focused Recruiting nowD0: inclusion visit * information * Realization of the ocular ultrasound (care) * Collection of consent * Realization of high resolution MRI with injection of contrast product (duration of 30 minutes) For the realization of the MRI, the contrast product used is the gadobutrol. T…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Heart surgery study questions routine use of ultrasound probe
Knowledge-focused CompletedThis goal of this study is to better understand when and where intraoperative transesophageal echocardiography (TEE) should (or should not) be used during coronary artery bypass graft (CABG) surgeries.
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Which blade size works best for intubation? large study seeks answers
Knowledge-focused CompletedEndotracheal intubation is a frequent procedure in the operating room but optimal Macintosh blade size remains unknown to date.
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Sepsis clot study reveals hidden danger
Knowledge-focused CompletedImpaired fibrinolysis in septic patients is associated with worse outcome. The present study investigates fibrinolysis shutdown in septic patients, defined as prolonged ClotPro® TPA lysis time at 30 minutes. The TPA lysis time reference range is established in a cohort of healthy…
Phase: NA • Sponsor: Policlinico Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Cochlear implant Users' speech skills tracked over time
Knowledge-focused CompletedThis is a retrospective study designed to collect long-term speech perception results for cochlear implants recipients using electro-acoustic-stimulation as measured in the clinical routine and to confirm the performance of sound processors associated with acoustic earhooks.
Sponsor: Advanced Bionics AG • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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COPD study aims to unlock clues behind immune cell drop during severe attacks
Knowledge-focused Recruiting nowThe goals of this observational study are to identify factors independently associated with admission eosinopenia in patients with a severe exacerbation of chronic obstructive pulmonary disease (COPD) and to determine when blood eosinophil count (BEC) will recover to baseline sta…
Sponsor: Northumbria Healthcare NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Drain or no drain? new study aims to cut unnecessary tubes after gallbladder surgery
Knowledge-focused CompletedThis study looks at when surgical drains are truly needed after laparoscopic gallbladder removal (laparoscopic cholecystectomy). Drains are sometimes placed during surgery to prevent fluid buildup or infection, but many studies show they are not always necessary. We reviewed 559 …
Sponsor: University of Baghdad • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Can zapping the brain help you learn faster?
Knowledge-focused CompletedThe purpose of this study is to compare the effectiveness of different repetitive Transcranial Magnetic Stimulation protocols for enhancing motor learning in healthy peolple.
Phase: NA • Sponsor: Neuron, Spain • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:02 UTC
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Gum disease could throw off your Body's daily rhythm, study finds
Knowledge-focused CompletedThis observational study aims to investigate whether periodontal inflammation is associated with alterations in the expression of circadian clock-related genes and proteins in gingival tissues. Circadian rhythms regulate many biological processes, including immune responses and i…
Sponsor: Inonu University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Helmet or facemask: which breathing aid wins for low oxygen?
Knowledge-focused CompletedThe optimal noninvasive management of acute hypoxemic respiratory failure is debated. Helmet noninvasive ventilation may be more effective than facemask noninvasive ventilation for these patients. Putatitve benefits of helmet use are the possibility to apply significantly higher …
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Do graphic warning labels on alcohol deter drinkers? new study investigates
Knowledge-focused CompletedThe goal of this study is to determine the effectiveness of pictorial warning labels (PWLs) featuring narrative (vs. non-narrative) content in communicating the cancer risk of alcohol. Participants will be randomized to view either three narrative or non-narrative PWLs. Key outco…
Phase: NA • Sponsor: University of Connecticut • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC