Simple workout may boost transplant rejection blood test

NCT ID NCT04656080

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether doing a hard exercise test before a blood draw can make the AlloSure test better at spotting heart transplant rejection. Researchers will test 27 heart transplant recipients, both with stable transplants and those showing signs of rejection. The goal is to see if exercise changes the levels of donor DNA in the blood, which could help doctors catch rejection earlier and more accurately.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could show that a simple exercise test before a blood draw makes rejection detection more accurate, possibly reducing the need for invasive biopsies.
What could go wrong
This is a very small, early-stage study with only 27 participants. It is designed to gather knowledge, not to prove a new treatment works. Results may not apply to all heart transplant patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor Scott & White health research institute

    RECRUITING

    Dallas, Texas, 75246, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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