Could one dose of antibiotics during nose surgery be enough?

NCT ID NCT04194216

ENROLLING_BY_INVITATION Disease control Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares giving a single dose of antibiotics during rhinoplasty (nose surgery) versus a full course of antibiotics after surgery. The goal is to see if the single dose works just as well at preventing infections. Over 800 adults having nose surgery will take part, and researchers will track infection rates between the two groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cephalexin or clindamycin (antibiotics)
What this could lead to: If successful, this could show that a single antibiotic dose during surgery is enough to prevent infections, reducing the need for post-surgery antibiotics.
What could go wrong: This is a large trial, but it only looks at infection rates in rhinoplasty. Results may not apply to other surgeries, and the best antibiotic approach may still depend on individual patient factors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Nasal Obstruction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NASAL OBSTRUCTION NASAL SURGICAL PROCEDURES

Contacts and locations

Locations

Facial Plastic and Reconstructive Surgery Clinic

Stanford, California, 94305, United States

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