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116076 trials found · Page 5493 of 5804
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Experimental cancer combo trial ends early – only 5 patients treated
Disease control TerminatedThis is a single arm study of RiMO-401 with radiation in patients with advanced tumors. A single escalation dose of RiMO-401 is intratumorally injected in a 3+3 study design to identify the recommended dose.
Phase: PHASE1 • Sponsor: Coordination Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 26, 2026 18:38 UTC
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Massive registry launches to track general anesthesia in C-Sections
Knowledge-focused Recruiting nowThe SOAP registry is a prospective, multicenter, electronic registry. The goal is to investigate the indications, mode of airway management, predisposing factors, and obstetric and anesthetic outcomes of pregnant patients who receive general anesthesia for cesarean delivery.
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Skip the fast? study tests if eating before surgery eases anxiety
Symptom relief Recruiting nowThe purpose of this study is to determine whether eating solid food prior to undergoing a wide awake local-only no tourniquet (WALANT) procedure reduces anxiety in patients or has any effect on outcomes. Patients will be split randomly into two groups and told whether to eat or f…
Phase: NA • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Ultrasound reveals safe drinking limits before surgery
Knowledge-focused CompletedThis study aims to evaluate the permissive amount and time limit of clear fluid intake for preoperative fasting.
Sponsor: SMG-SNU Boramae Medical Center • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Surgeons' tools may leave a digital fingerprint
Knowledge-focused Recruiting nowThe purpose of this prospective, single center study is to verify the hypothesis that each type of intervention creates a specific data pattern like a digital "fingerprint". This fingerprint offers the possibility to identify specific workflows of surgical procedures but also to …
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Single-Patient trial tests safety of ATGAM for rare blood disorder
Disease control OngoingThe objective of this study is to confirm the safety of ATGAM in patients with moderate to severe aplastic anemia under the actual use in Japan. The registration criteria is patients with moderate to severe aplastic anemia who receive ATGAM. The observation period is 24 weeks (…
Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Can Peer-Led training stop cyberbullying? new study tests it
Knowledge-focused CompletedThis study aims to explore ways to reduce cyberbullying among male high school students in Tehran by comparing two types of training: direct instruction from a psychologist and peer-led training. Cyberbullying is a serious problem that affects many teenagers, causing stress, emot…
Phase: NA • Sponsor: Ahvaz Jundishapur University of Medical Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Sticky situation: new study tests which prosthetic glue leaves the least mess on skin
Knowledge-focused CompletedThis pilot interventional in vivo study aims to quantitatively evaluate and compare the amount of adhesive residue left on the skin following removal of extraoral maxillofacial prosthetic adhesives. Five commercially available adhesives will be tested using standardized silicone …
Phase: NA • Sponsor: Amrita Vishwa Vidyapeetham • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Nighttime oxygen dips common after severe injury, study finds
Knowledge-focused CompletedThe goal of this observational study is to investigate the occurrence of hypoxemia (an abnormally low concentration of oxygen in the blood) in trauma patients within the first 24 hours of hospital admission following arrival to a trauma center. The main questions the study aims …
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Step-Ups vs running: which boosts heart health more?
Knowledge-focused CompletedThis study compares the effects of two aerobic exercise methods - loaded step-up exercise and treadmill running - on cardiovascular fitness, leg strength, heart rate variability, and recovery in sedentary adult males. Both exercise groups will train at 80-85% of maximum heart rat…
Phase: NA • Sponsor: Ankara University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Parenting program shows promise in strengthening families
Knowledge-focused CompletedThe goal of this study is to evaluate the effectiveness of positive parenting programs targeted to parents of toddlers, children and adolescents carried out in Cantabria (Spain). We will collect information from the participants before the intervention, in the last session of th…
Phase: NA • Sponsor: University of Seville • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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One-Leg cycling study explores new exercise clues for COPD
Knowledge-focused CompletedCOPD presents not only respiratory symtoms but also vascular or muscle dysfunction. Exercise training is important for aerobic performance increasing. Generally results show exercise training with both lower limb. Increaed arterial stiffness and muscle oxygenation are observed in…
Phase: NA • Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Sweat and chill: could sauna and cold baths tame stress-related blood pressure spikes?
Knowledge-focused CompletedIt is well-accepted that an exaggerated blood pressure (BP) response to physical stress has a prognostic value, indicating a higher cardiovascular risk (e.g., sudden cardiac death, myocardial infarction, future hypertension, and left ventricular hypertrophy). However, there is a …
Phase: NA • Sponsor: Western Norway University of Applied Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New thermometer put to the test in 373 people
Diagnosis CompletedThe purpose of this document is to validate the clinical accuracy of the TIMMY3 thermometry module, integrated into host device CVSM, according to ISO 80601-2-56:2017 + A1 2018.
Phase: NA • Sponsor: Baxter Healthcare Corporation • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC
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Tiny study tests if DNA can decide how much thyroid to remove
Knowledge-focused CompletedIdeal surgical extent for differentiated thyroid cancer remains unclear. Routine use of molecular analysis in biopsy-proven thyroid cancer could provide important prognostic information to help guide extent of surgery - thyroid lobectomy versus total thyroidectomy. This is a pilo…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Real-World watch: is zavicefta safe for tough infections?
Knowledge-focused Recruiting nowThe purpose of this study is to learn about the safety and effectiveness of Zavicefta once released into the markets in Korea. This study is to learn about Zavicefta in patients with difficult types of infections in the abdomen, urinary tract and pneumonia which could have come f…
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:53 UTC
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Gut bugs could predict chemo success in rectal cancer
Knowledge-focused TerminatedThis is an observational, single-centre study (RIPH3) for patients with rectal cancer soon to be treated with chemotherapy (+/- neo-adjuvant radio-chemotherapy) looking at the relationship between the composition of the gut microbiota before treatment and the tumour response afte…
Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Stroke's hidden toll: brain scans reveal emotion perception changes
Knowledge-focused TerminatedThis monocentric physiological study will evaluate the neural bases of visual recognition of emotions in stroke patients vs. healthy controls using MRI (functional and structural connectivity) and EEG.
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Trauma colon injury study aims to improve surgical outcomes
Knowledge-focused Recruiting nowThis retrospective data repository will serve as a means to aggregate and analyze best practices as relative to traumatic colon injury outcomes.
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Missing hand muscle may shield against dupuytren disease
Knowledge-focused CompletedDupuytren disease is a medical condition characterized by the painless formation of nodules in the palm of the hand. Cords are formed on the palmar fascia, a connective tissue sheet in the palm of the hand. This fascia is seen as the vestigial remnant of the palmaris longus tendo…
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC