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127005 trials found · Page 5460 of 6351
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Opioid use may weaken flu shots in HIV patients, study suggests
Knowledge-focused OngoingThe purpose of this research is to evaluate blood samples from HIV infected and non-HIV infected people opioid and non opioid users to understand how opioid affect the immune responses (body defenses against infection) to the flu vaccine.
Phase 4 • Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Sniffing your way back: smell training tested for COVID-19 scent loss
Symptom relief CompletedThe purpose of this study is to evaluate efficiency of two months of olfactive training on olfactory and taste loss secondary to covid-19. We will compare 2 groups : olfactive training group versus no olfactive training group.
Sponsor: Centre Hospitalier Universitaire de la Guadeloupe • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Blood test may tell if kids have outgrown food allergies
Knowledge-focused CompletedThe study objectives are : Determine standards of plasma levels of casein-specific immunoglobulin G4 (IgG4) and egg-specific immunoglobulin G4 (IgG4) as a function of age, in non-allergic children, in allergic children, and in cured former allergic patients. Analyze the plasma …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Blood test could spot cervical cancer return earlier
Knowledge-focused OngoingThis study collects blood samples to determine if the DNA of HPV that causes cervical cancer can be detected in patients with cervical cancer that is new (primary), has come back (recurrent), or has spread to other places in the body (metastatic) and are undergoing treatment with…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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HPV booster study tracks immunity years later
Knowledge-focused OngoingThis is an extended follow-up study to follow-up study participants who received 1 booster dose of Gardasil 9 in the "HPV vaccine delayed booster trial." This was a prospective, single-arm, open-label, non-randomized, phase IIa trial among 9-11 year-old girls and boys to determin…
Sponsor: University of Arizona • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Robots take on breast cancer surgery in tiny pilot trial
Disease control OngoingThis is a pilot study to determine safety, efficacy, and potential risks of robot assisted nipple sparing mastectomy (RNSM), by utilizing the daVinci surgical system.
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Cancer Patients' COVID-19 trial halted after just 4 volunteers
Disease control Stopped earlyThis phase I/IIa trial studies the best dose and side effects of rintatolimod and interferon (IFN) alpha-2b in treating cancer patients with COVID-19 infection. Interferon alpha is a protein important for defense against viruses. It activates immune responses that help to clear v…
Phase 1/2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Beetroot and caffeine combo tested for cycling edge
Symptom relief CompletedThis study is investigating the independent and combined effects of acute dietary nitrate and caffeine supplementation on performance during a 3-minute all-out cycling test in trained male cyclists. In a randomized, double-blind, placebo-controlled, crossover design, participants…
Sponsor: Lindenwood University • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Scientists probe cell secrets behind diabetes heart risk
Knowledge-focused Recruiting nowThis study aims to isolate endothelial progenitor cells (EPCs) from participants with type 2 diabetes (T2D) and cardiovascular complications and to comprehensively characterize EPC dysfunction. Specifically, the study will evaluate maladaptive angiocrine signaling, calcium signal…
Sponsor: Weill Cornell Medical College in Qatar • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Collagen patch after oral cancer surgery: does it help you swallow and speak?
Knowledge-focused CompletedThis study tend to evaluate postoperative phonation and swallowing after oncologic surgery of the oral cavity or oropharynx with application of a collagen matrix (Tachosil®). Patients are asked to complete a questionnaire the day before the surgery and at 1 and 6 months after.
Sponsor: SAYAH Charline • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Could a simple drink help clear confusion in hospitalized seniors?
Symptom relief Recruiting nowThe investigators have developed a proprietary blend of amino acids that they think will help to prevent or reduce the severity of delirium in older adults (60 years and older) who are hospitalized for certain infections. In this study, up to 60 people will be enrolled.20 will be…
Sponsor: University of Arkansas • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Texts and resources may close language gap for latino kids
Knowledge-focused CompletedThis study tests the extent to which tailored outreach text messages that provide a cue to action and an intervention that enhances access to poverty-reducing resources, in combination with standard primary care literacy promotion, can improve child language and social- emotional…
Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Scientists track how prostate cancer drug travels in bones
Knowledge-focused CompletedIn this study researcher want to gain more information on how the study drug (radium-223) is distributed in the bone, particularly in the tumor free bone in participants with prostate cancer. The study plans to enroll 60 patients with the age of at least 18 years and suffering fr…
Phase 1 • Sponsor: Bayer • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:58 UTC
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Reading app trial aims to boost literacy in kids with dyslexia
Knowledge-focused OngoingThe current project will carry out a large-scale, randomized controlled trial (RCT) to examine the effectiveness of a home-administered technology-based treatment for reading disability (GraphoLearn) in a diagnostically diverse children with reading disability (ages 6.0-10.00). T…
Sponsor: University of Connecticut • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:15 UTC
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Brain training shows promise for seniors with depression
Symptom relief CompletedThis research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with antidepressants. The investigators are also interested in whether participating in the trea…
Sponsor: UConn Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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When you eat salt may matter as much as how much
Knowledge-focused CompletedExperimental data have shown that timing of sodium intake impacts diurnal patterns of sodium excretion. The purpose of this study is to test the hypothesis that the time of day for salt intake impacts (1) blood pressure rhythms and urinary sodium excretion and (2) circadian timin…
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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Knee tear repair device tested, but study stopped early
Disease control Stopped earlyThe purpose of this study is to understand the benefits and safety of the NOVOSTITCH PRO Meniscal Repair (NOVOSTITCH PRO) system. The meniscus is a tissue in the knee joint. The NOVOSTITCH PRO is used during surgery to fix meniscus tears in the knee. It is unknown whether fixing …
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Stickers for steps: new study tests fun exercise program for young cancer patients
Symptom relief Recruiting nowThis clinical trial studies how well an exercise program (Totally Excited About Moving, Mobility, and Exercise \[TEAM Me\]) affects the exercise and dietary habits of pediatric and adolescents and young adults with cancer undergoing a blood stem cell transplant. TEAM Me is an exe…
Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Smartwatches and nerve tests aim to unlock spinal injury secrets
Knowledge-focused Recruiting nowThis study looks to characterize gradients of dysfunction in the autonomic nervous system after spinal cord injury. The autonomic nervous system plays key roles in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals with spinal cord inju…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Brain zaps may unlock fibromyalgia pain secrets
Knowledge-focused OngoingThis project is being conducted to evaluate the impact of explosive synchronization (ES) and its treatment with non-invasive brain stimulation in fibromyalgia (FM). The study design has three components, however, only 2 aims are enrolling participants. The first part (Aim1) is a …
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC