Brain training shows promise for seniors with depression

NCT ID NCT04790630

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether computerized brain-training activities could improve thinking skills and depression symptoms in older adults who were already taking antidepressants. Thirty-eight participants completed the program, and researchers measured changes in mental flexibility, memory, and depression severity. The goal was to see if a non-drug approach could offer extra benefits for this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

computerized brain-training activities

What this could lead to

If it works, this could point toward a non-drug way to boost thinking and mood in older adults with depression.

What could go wrong

This was a small, early study with only 38 people. The brain-training may not work for everyone, and benefits might be modest or short-lived.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UConn Health

    Farmington, Connecticut, 06030, United States