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127005 trials found · Page 5444 of 6351
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New kidney machine for tiny tots under scrutiny
Knowledge-focused OngoingThe post market surveillance study will employ a prospective, multi-center, single-arm, observational design to capture data on children who undergo CRRT using the Carpediem™ system. Participating clinicians will manage subjects in accordance to their local standard of care pract…
Sponsor: Mozarc Medical US LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Teaching parents about food may boost growth in kids after heart surgery
Knowledge-focused CompletedThe Effect of Individualized Nutrition Training Given to the Families of Children with Congenital Heart Disease (CHD) in the Post-Operative Period on their Growth and Development This study was conducted experimentally to determine the effects of individualized nutrition training…
Sponsor: Cukurova University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Breathing new life into lung monitoring: MRI with inhaled gas tracks cystic fibrosis
Knowledge-focused Recruiting nowThe purpose of this study is to look at lung ventilation in people with cystic fibrosis over time (1 year) using magnetic resonance imaging (MRI) with an inhaled contrast gas, and compare these measures to lung function assessed by spirometry and multiple breath nitrogen washout.…
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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New insulin fiasp tested in everyday diabetes care
Disease control CompletedThis study is to investigate the effects of Fiasp®, a mealtime insulin, in patients with diabetes mellitus. The purpose of this study is to collect information about Fiasp®, which is prescribed to the participants by their doctors. Participants will administer Fiasp® as prescribe…
Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Lidocaine levels measured in brain tumors during surgery
Knowledge-focused CompletedThis clinical trial measures the amount and effect of lidocaine injected into patients with glioblastoma while they are undergoing surgical removal of their brain tumors. Lidocaine is a substance used to relieve pain by blocking signals at the nerve endings in skin. Information g…
Phase 1 • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Can big data crack the code of inflammatory bowel disease?
Knowledge-focused By invitation onlyThis study aims to establish an integrated cohort of patients with inflammatory bowel disease (IBD) from Seoul National University Hospital, Seoul National University Boramae Medical Center, and Seoul National University Bundang Hospital. Through this cohort, we seek to develop a…
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:58 UTC
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Brain scans may predict depression relapse
Knowledge-focused OngoingThis study investigates how remitted individuals with past major depressive disorder (MDD) make approach-avoidance decisions and which brain regions are implicated in such decisions. Information collected through MRI and behavioral tasks will be used to predict depressive symptom…
Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Radiation-Free 3D scans could replace CT for cancer treatment planning
Knowledge-focused CompletedThis study evaluates if three dimensional (3D) surface images can be used instead of the standard computed tomography (CT) scans for treatment planning in electron radiation therapy. 3D scanning has previously been used by several groups to design patient-specific devices to be 3…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Heat wave study reveals hidden heart risks for seniors
Knowledge-focused CompletedThe purpose of this study is to assess the cardiovascular responses of the elderly to heat wave conditions
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Breathing in a special gas reveals hidden lung damage in transplant patients
Knowledge-focused Stopped earlyThis study will use Magnetic Resonance Imaging (MRI) to study the lungs of 90 volunteers using the inhaled contrast agent, hyperpolarized xenon-129. Once inhaled, this gas can provide information to imagers regarding lung functionality across specific regions of the lungs by asse…
Sponsor: Xemed LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Which ankle surgery gets athletes back in the game faster?
Knowledge-focused CompletedReal-life, observational, monocentric, prospective, longitudinal study, carried out at the European Center for Sports Rehabilitation (CERS), France.
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Mediterranean diet tested to prevent weight gain after liver transplant
Disease control Recruiting nowThe purpose of this study is to study the effects of a structured Mediterranean dietary program on prevention of weight gain, promotion of heart health and prevention of fatty liver disease after liver transplantation.
Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Can a simple urine test prevent kidney failure in sepsis?
Disease control Stopped earlyBiomarkers that provide an early indicator of kidney stress could be useful in clinical practice to detect silent episodes of acute kidney injury (AKI) or for early identification of subjects at risk of AKI. Two urinary biomarkers have been identified as early indicators of AKI. …
Sponsor: BioMérieux • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Cancer combo trial halted early: what we learned
Disease control Stopped earlyThis study is an open, multi-center clinical trial, the purpose is to study the safety and preliminary efficacy of Donafenib combined with KN046 in subjects with Advanced Gastrointestinal Tumors.
Phase 1/2 • Sponsor: Suzhou Zelgen Biopharmaceuticals Co.,Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Saliva test may predict teen concussion recovery time
Knowledge-focused OngoingThe purpose of this study is to identify changes in salivary micro ribonucleic acid (miRNA) levels that are predictive of symptom duration and character following mild traumatic brain injury (mTBI) in children.
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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New insomnia pill passes first safety check in healthy volunteers
Symptom relief CompletedMultiple Dose Safety, Tolerability, PK ,PD and Food Effect Study of HEC83518 in Healthy Subjects
Phase 1 • Sponsor: Sunshine Lake Pharma Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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C-Section pain relief: does ketorolac raise bleeding risk?
Knowledge-focused CompletedCesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption. The effect of NSAIDs on healthy volunteers results i…
Phase 4 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Could a baby's birth sac help heal your neck after surgery?
Symptom relief By invitation onlyThe primary objective of this study is to obtain evidence of the effectiveness of AlloWrap Amniotic Membrane in the reduction of soft tissue swelling in two-level ACDF procedures.
Sponsor: AlloSource • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Brain imaging study seeks clues to childhood epilepsy
Knowledge-focused CancelledThe investigators are recruiting children with Rolandic epilepsy and children without epilepsy (aged 4 years old and above) for a non-invasive brain imaging study using Magnetic Resonance Imaging (MRI), Magnetoencephalography/Electroencephalography (MEG/EEG), and experimental tas…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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New chest surgery shows promise for trauma patients
Knowledge-focused CompletedThe purpose of this study is to assess the outcome of a muscle sparing, minimally invasive open surgical technique for unstable ribcage injuries after trauma. The investigators will compare the results from the study participants to a historical cohort who were operated with a di…
Sponsor: Sahlgrenska University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC