Saliva test may predict teen concussion recovery time

NCT ID NCT04582682

Ongoing Knowledge-focused Sponsor: Milton S. Hershey Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 07, 2026 · Updated 3 times

Summary

This study tracks 750 teens aged 13-18 with mild concussions to see if changes in their saliva can predict how long symptoms last. Researchers will check for persistent symptoms 30 days after injury. The goal is to find biological markers that help doctors personalize recovery plans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict which teens will have long-lasting concussion symptoms, leading to better follow-up care.
What could go wrong: This is an observational study, not a treatment trial. It may not find clear predictors, and results may not apply to all teens.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Brain Concussion traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONCUSSION, MILD

Contacts and locations

Locations

Boston Children's Hosptial

Boston, Massachusetts, 02115, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Penn State Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
SUNY Upstate Medical University

Syracuse, New York, 13210, United States
Weill Cornell Medicine/ New York Presbyterian Hospital

New York, New York, 10021, United States

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