Breathing new life into lung monitoring: MRI with inhaled gas tracks cystic fibrosis

NCT ID NCT06057714

Recruiting now Knowledge-focused Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests a new MRI method that uses an inhaled gas to create detailed images of lung ventilation in people with cystic fibrosis. Researchers will track 30 adults with mild lung disease over a year, comparing the MRI results to standard breathing tests. The goal is to see if this technique can better detect changes in lung function, especially during flare-ups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Perfluoropropane (PFP) gas
What this could lead to: If successful, this could lead to a new, more detailed way to monitor lung health in cystic fibrosis, helping doctors detect problems earlier.
What could go wrong: This is a small, early-stage imaging study with no direct treatment benefit. The new MRI method may not prove more useful than existing tests.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CYSTIC FIBROSIS VENTILATORY DEFECT

Contacts and locations

Locations

Univeristy of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27514, United States

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