New kidney machine for tiny tots under scrutiny

NCT ID NCT04608149

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows about 36 children weighing 2.5-10 kg who have acute kidney injury or fluid overload and are treated with the Carpediem continuous renal replacement therapy system. Researchers will track survival, kidney recovery, and hospital stay lengths to see how well the device works in real-world intensive care settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Carpediem™ system (continuous renal replacement therapy device)

What this could lead to

If successful, this study could confirm that the Carpediem system is safe and effective for treating kidney injury and fluid overload in small children.

What could go wrong

This is an observational study with no control group, so it cannot prove the device works better than other treatments. Results may not apply to all children.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Golisano Children's Hospital

    Rochester, New York, 14642, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Seattle Children's

    Seattle, Washington, 98103, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • University of Iowa Healthcare

    Iowa City, Iowa, 52252, United States