New kidney machine for tiny tots under scrutiny

NCT ID NCT04608149

Ongoing Knowledge-focused Sponsor: Mozarc Medical US LLC Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows about 36 children weighing 2.5-10 kg who have acute kidney injury or fluid overload and are treated with the Carpediem continuous renal replacement therapy system. Researchers will track survival, kidney recovery, and hospital stay lengths to see how well the device works in real-world intensive care settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Carpediem™ system (continuous renal replacement therapy device)
What this could lead to: If successful, this study could confirm that the Carpediem system is safe and effective for treating kidney injury and fluid overload in small children.
What could go wrong: This is an observational study with no control group, so it cannot prove the device works better than other treatments. Results may not apply to all children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Edema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE KIDNEY INJURY FLUID OVERLOAD

Contacts and locations

Locations

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Golisano Children's Hospital

Rochester, New York, 14642, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Seattle Children's

Seattle, Washington, 98103, United States
Texas Children's Hospital

Houston, Texas, 77030, United States
University of Iowa Healthcare

Iowa City, Iowa, 52252, United States

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